Skip to main content
  • AACR Publications
    • Blood Cancer Discovery
    • Cancer Discovery
    • Cancer Epidemiology, Biomarkers & Prevention
    • Cancer Immunology Research
    • Cancer Prevention Research
    • Cancer Research
    • Clinical Cancer Research
    • Molecular Cancer Research
    • Molecular Cancer Therapeutics

AACR logo

  • Register
  • Log in
  • My Cart
Advertisement

Main menu

  • Home
  • About
    • The Journal
    • AACR Journals
    • Subscriptions
    • Permissions and Reprints
  • Articles
    • OnlineFirst
    • Current Issue
    • Past Issues
    • CEBP Focus Archive
    • Meeting Abstracts
    • Progress and Priorities
    • Collections
      • COVID-19 & Cancer Resource Center
      • Disparities Collection
      • Editors' Picks
      • "Best of" Collection
  • For Authors
    • Information for Authors
    • Author Services
    • Best of: Author Profiles
    • Informing Public Health Policy
    • Submit
  • Alerts
    • Table of Contents
    • Editors' Picks
    • OnlineFirst
    • Citation
    • Author/Keyword
    • RSS Feeds
    • My Alert Summary & Preferences
  • News
    • Cancer Discovery News
  • COVID-19
  • Webinars
  • Search More

    Advanced Search

  • AACR Publications
    • Blood Cancer Discovery
    • Cancer Discovery
    • Cancer Epidemiology, Biomarkers & Prevention
    • Cancer Immunology Research
    • Cancer Prevention Research
    • Cancer Research
    • Clinical Cancer Research
    • Molecular Cancer Research
    • Molecular Cancer Therapeutics

User menu

  • Register
  • Log in
  • My Cart

Search

  • Advanced search
Cancer Epidemiology, Biomarkers & Prevention
Cancer Epidemiology, Biomarkers & Prevention
  • Home
  • About
    • The Journal
    • AACR Journals
    • Subscriptions
    • Permissions and Reprints
  • Articles
    • OnlineFirst
    • Current Issue
    • Past Issues
    • CEBP Focus Archive
    • Meeting Abstracts
    • Progress and Priorities
    • Collections
      • COVID-19 & Cancer Resource Center
      • Disparities Collection
      • Editors' Picks
      • "Best of" Collection
  • For Authors
    • Information for Authors
    • Author Services
    • Best of: Author Profiles
    • Informing Public Health Policy
    • Submit
  • Alerts
    • Table of Contents
    • Editors' Picks
    • OnlineFirst
    • Citation
    • Author/Keyword
    • RSS Feeds
    • My Alert Summary & Preferences
  • News
    • Cancer Discovery News
  • COVID-19
  • Webinars
  • Search More

    Advanced Search

Highlights

Highlights of This Issue

DOI:  Published July 2016
  • Article
  • Info & Metrics
  • PDF
Loading

The Aging Cancer Survivor Population

Bluethmann et al. Page 1029

Cancer incidence and survival data from the Surveillance, Epidemiology, and End Results (SEER) Program were used by Bluethmann and colleagues to estimate current cancer prevalence. The authors also report cancer projections using U.S. Census Bureau data and the Prevalence Incidence Approach Model. In 2016, there were 15.5 million cancer survivors living in the U.S. and the prevalent population is projected to reach 26.1 million by 2040, with 73% of survivors being 65 years and older. Older adults now constitute the majority of cancer survivors and will continue to dominate the survivor population over the next 24 years.

Circulating Cancer-Associated Macrophages as Biomarkers

Adams et al. Page 1037

Circulating cancer-associated macrophage-like cells (CAML) are associated with the presence of solid malignancies. Adams and colleagues measured CAMLs prospectively to ascertain their prevalence, specificity, and sensitivity to breast disease status at clinical presentation. CAMLs were found in 93% of known malignant patients, but none were detected in the healthy controls. In subjects undergoing core biopsy for initial diagnosis, CAMLs were found in 88% of subjects with invasive carcinoma. These preliminary studies suggest that the presence of CAMLs may differentiate patients with malignant disease, benign breast conditions, and healthy individuals.

Telomere Length and Chronic Lymphocytic Leukemia

Ojha et al. Page 1043

Chronic lymphocytic leukemia (CLL) is the most common leukemia in the Western world. Shorter mean telomere length in leukemic cells has been associated with more aggressive disease, and polymorphisms in telomere maintenance genes impact telomere length and contribute to CLL susceptibility. Ojha and colleagues used genome data from patients with CLL and healthy control populations and examined eight single nucleotide polymorphisms (SNPs) in genes definitively associated with leukocyte telomere length (LTL). Three of the eight LTL-associated SNPs were associated with CLL risk. The role of telomere length in CLL etiology may be distinct from its role in disease progression.

Selenium/Vitamin E Supplementation, Genotype, and Prostate Cancer

Chan et al. Page 1050

Randomized trials supported the hypothesis that selenium and vitamin E lower prostate cancer risk, but the Selenium and Vitamin E Cancer Prevention Trial (SELECT) showed no benefit of either supplement. To investigate if genetic variants involved in selenium or vitamin E metabolism or transport may underlie the complex associations of selenium/vitamin E and prostate cancer, Chan and colleagues undertook a case–cohort study of SELECT participants randomized to placebo, selenium, or vitamin E. This study found statistically significant interactions between selenium assignment, SNPs in CAT, SOD2, PRDX6, SOD3, and TXNRD2, and high-grade prostate cancer risk, indicating that the effect of selenium or vitamin E supplementation on high-grade prostate cancer risk may vary by genotype.

  • ©2016 American Association for Cancer Research.
PreviousNext
Back to top
Cancer Epidemiology Biomarkers & Prevention: 25 (7)
July 2016
Volume 25, Issue 7
  • Table of Contents
  • Table of Contents (PDF)

Sign up for alerts

View this article with LENS

Open full page PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for sharing this Cancer Epidemiology, Biomarkers & Prevention article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Enter multiple addresses on separate lines or separate them with commas.
Highlights of This Issue
(Your Name) has forwarded a page to you from Cancer Epidemiology, Biomarkers & Prevention
(Your Name) thought you would be interested in this article in Cancer Epidemiology, Biomarkers & Prevention.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
Highlights of This Issue
Cancer Epidemiol Biomarkers Prev July 1 2016 (25) (7) 1007;

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
Highlights of This Issue
Cancer Epidemiol Biomarkers Prev July 1 2016 (25) (7) 1007;
del.icio.us logo Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • The Aging Cancer Survivor Population
    • Circulating Cancer-Associated Macrophages as Biomarkers
    • Telomere Length and Chronic Lymphocytic Leukemia
    • Selenium/Vitamin E Supplementation, Genotype, and Prostate Cancer
  • Info & Metrics
  • PDF
Advertisement

Related Articles

Cited By...

More in this TOC Section

  • Selected Articles from This Issue
  • Selected Articles from This Issue
  • Selected Articles from This Issue
Show more Highlights
  • Home
  • Alerts
  • Feedback
  • Privacy Policy
Facebook   Twitter   LinkedIn   YouTube   RSS

Articles

  • Online First
  • Current Issue
  • Past Issues

Info for

  • Authors
  • Subscribers
  • Advertisers
  • Librarians

About Cancer Epidemiology, Biomarkers & Prevention

  • About the Journal
  • Editorial Board
  • Permissions
  • Submit a Manuscript
AACR logo

Copyright © 2021 by the American Association for Cancer Research.

Cancer Epidemiology, Biomarkers & Prevention
eISSN: 1538-7755
ISSN: 1055-9965

Advertisement