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Cancer Epidemiology, Biomarkers & Prevention
Cancer Epidemiology, Biomarkers & Prevention
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Trends in Endometrial Cancer Incidence by Race and Histology with a Correction for the Prevalence of Hysterectomy, SEER 1992 to 2008

Patricia M. Jamison, Anne-Michelle Noone, Lynn A.G. Ries, Nancy C. Lee and Brenda K. Edwards
Patricia M. Jamison
1National Cancer Institute, Surveillance, Epidemiology, and End Results Program, Bethesda, Maryland; and 2Office on Women's Health, Office of the Secretary, U.S. Department of Health and Human Services, Washington, District of Columbia
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Anne-Michelle Noone
1National Cancer Institute, Surveillance, Epidemiology, and End Results Program, Bethesda, Maryland; and 2Office on Women's Health, Office of the Secretary, U.S. Department of Health and Human Services, Washington, District of Columbia
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Lynn A.G. Ries
1National Cancer Institute, Surveillance, Epidemiology, and End Results Program, Bethesda, Maryland; and 2Office on Women's Health, Office of the Secretary, U.S. Department of Health and Human Services, Washington, District of Columbia
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Nancy C. Lee
1National Cancer Institute, Surveillance, Epidemiology, and End Results Program, Bethesda, Maryland; and 2Office on Women's Health, Office of the Secretary, U.S. Department of Health and Human Services, Washington, District of Columbia
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Brenda K. Edwards
1National Cancer Institute, Surveillance, Epidemiology, and End Results Program, Bethesda, Maryland; and 2Office on Women's Health, Office of the Secretary, U.S. Department of Health and Human Services, Washington, District of Columbia
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DOI: 10.1158/1055-9965.EPI-12-0996 Published February 2013
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    Figure 1.

    Estimated hysterectomy prevalence over time among white and black women age 50+. Error bars represent the 95% CI. Source: BRFSS public use file.

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    Figure 2.

    Age-adjusted endometrial cancer incidence rates by race, corrected and uncorrected for hysterectomy prevalence among women age 50+, SEER from 1992–2008. The APC is shown next to the regression line and the asterisk indicates APC is statistically significant, P < 0.05. Source: incidence data from SEER 13 areas covering about 14% of the U.S. population (CT, HI, IA, NM, UT, metropolitan Detroit, metropolitan Atlanta, rural GA, Seattle-Puget Sound, San Francisco-Oakland, San Jose-Monterey, and Los Angeles). Hysterectomy prevalence data from BRFSS public use file.

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    Figure 3.

    Age-adjusted endometrial cancer incidence rates among black and white women by subtype, corrected and uncorrected for hysterectomy prevalence among women age 50+, SEER from 1992 to 2008. The APC is shown next to the regression line and the asterisk indicates APC is statistically significant, P < 0.05. A, type I endometrial cancer; B, type II endometrial cancer; C, malignant mixed Mullerian tumors; D, other histologic types. Source: incidence data from SEER 13 areas covering about 14% of the U.S. population (CT, HI, IA, NM, UT, metropolitan Detroit, metropolitan Atlanta, rural GA, Seattle-Puget Sound, San Francisco-Oakland, San Jose-Monterey, and Los Angeles).

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  • Table 1.

    Age-adjusted endometrial cancer incidence rates by race and subtype, corrected and uncorrected for hysterectomy prevalence among women 50+, SEER 1992 to 2008

    TypeRaceNo. of casesUncorrected rateRate ratioCorrected rateRate ratio
    All
    White57,96678.81.00136.01.00
    Black4,98060.90.77115.50.85
    API4,64247.50.6067.40.50
    Hispanica4,80251.00.6582.30.61
    Type I
    White48,70266.31.00114.21.00
    Black2,99336.40.5569.00.60
    API3,75738.30.5854.10.47
    Hispanica3,77939.60.6063.80.56
    Type II
    White3,7605.01.008.91.00
    Black82010.22.0419.42.18
    API3483.60.725.30.60
    Hispanica4144.60.927.70.87
    Malignant mixed Mullerian tumors
    White25113.31.005.91.00
    Black6277.82.3614.82.51
    API2202.30.703.40.58
    Hispanica2612.90.884.90.83
    Other
    White29934.11.007.01.00
    Black5406.51.5912.31.76
    API3173.30.804.60.66
    Hispanica3483.60.885.80.83

    NOTE: ICD-O-3 histology codes for type I: 8050, 8140–8141, 8143, 8210–8211, 8260–8263, 8323, 8340, 8380–8381, 8440, 8470–8471, 8480–8481, 8490, 8550, 8560, 8570, 8571–8573.

    Type II: 8310, 8441, 8460–8462.

    Malignant mixed Mullerian: 8950–8951, 8980–8981.

    Other: All other invasive endometrial cancers.

    Source: incidence data from Surveillance, Epidemiology, and End Results (SEER) 13 areas covering about 14% of the U.S. population (CT, HI, IA, NM, UT, metropolitan Detroit, metropolitan Atlanta, rural GA, Seattle-Puget Sound, San Francisco-Oakland, San Jose-Monterey, and Los Angeles).

    Hysterectomy prevalence data from BRFSS public use file.

    • ↵aHispanic is not mutually exclusive from white, black, and Asian Pacific Islander (API).

Additional Files

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    Files in this Data Supplement:

    • Appendix A - PDF file - 40K, Hysterectomy Prevalence by Age, Race and Year, 1992 to 2008, BRFSS
    • Appendix B - PDF file - 26K, Estimated Hysterectomy Prevalence over Time for Women Age 50+ by Race and Ethnicity, NHIS
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Cancer Epidemiology Biomarkers & Prevention: 22 (2)
February 2013
Volume 22, Issue 2
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Trends in Endometrial Cancer Incidence by Race and Histology with a Correction for the Prevalence of Hysterectomy, SEER 1992 to 2008
Patricia M. Jamison, Anne-Michelle Noone, Lynn A.G. Ries, Nancy C. Lee and Brenda K. Edwards
Cancer Epidemiol Biomarkers Prev February 1 2013 (22) (2) 233-241; DOI: 10.1158/1055-9965.EPI-12-0996

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Trends in Endometrial Cancer Incidence by Race and Histology with a Correction for the Prevalence of Hysterectomy, SEER 1992 to 2008
Patricia M. Jamison, Anne-Michelle Noone, Lynn A.G. Ries, Nancy C. Lee and Brenda K. Edwards
Cancer Epidemiol Biomarkers Prev February 1 2013 (22) (2) 233-241; DOI: 10.1158/1055-9965.EPI-12-0996
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