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Cancer Epidemiology, Biomarkers & Prevention
Cancer Epidemiology, Biomarkers & Prevention
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CEBP Focus: Cancer Survivorship Research

Economic Burden of Cancer in the United States: Estimates, Projections, and Future Research

K. Robin Yabroff, Jennifer Lund, Deanna Kepka and Angela Mariotto
K. Robin Yabroff
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Jennifer Lund
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Deanna Kepka
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Angela Mariotto
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DOI: 10.1158/1055-9965.EPI-11-0650 Published October 2011
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    Figure 1.

    Monthly costs of care for colorectal cancer patients by length of survival.

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    Figure 2.

    Incidence and prevalence costs of cancer care.

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    Figure 3.

    A, estimates of the national expenditures for cancer care in the United States in 2010 (in billions of dollars), by cancer site and phase of care. B, estimates of the proportion of national expenditures for cancer care in the United States in 2010 (in billions of dollars), by cancer site and phase of care.

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    Figure 4.

    Estimates of national expenditures for selected cancers in 2010 and 2020: impact of assumptions about trends in incidence, survival, and costs of care.

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  • Table 1.

    Characteristics of selected data sources/research resources in the United States for estimating burden of cancer

    DescriptionSEER-MedicareMEPSH-CUPMCBSCRN
    SEER tumor registries linked to Medicare claimsNational household, medical provider, and insurance surveyInpatient discharge data from sampled hospitalsNational survey linked to Medicare claimsResearch centers in managed care organizations
    Data characteristics
     National or nationally representativeGeographically defined√√√Geographically defined
     Individual-level longitudinal data√5 panels over 2 y√√
     Approximate number of cancer survivors in 2007>1,000,000<2,000>1,000,000<2,000>400,000
     Duration of informationMedicare eligibility through death2 yHospital admission through dischargeMultiple yearsEnrollment through disenrollment or death
     Health insurance typeMedicare fee-for-service onlyAll payorsAll payorsAll payorsManaged care only
    Patients' information
     Age distributionAged 65+ or disabled (any age)Aged 18+All agesAged 65+ or disabled (any age)All ages
     Information about patients without cancerIn cancer registry regions√√√√
    Cancer information
     Cancer diagnosisRegistry, procedure, or diagnosis codesSelf-report, procedure, or diagnosis codesProcedure or diagnosis codesSelf-report, procedure, or diagnosis codesRegistry, procedure, or diagnosis codes
     Stage at diagnosis√√
     Treatment√√Inpatient hospital only√√
    Type of cost estimate
     Incidence√√
     Prevalence in a specific year√√√√√
    Direct medical cost components
     Hospital√√√√√
     Physician and other outpatient services√√√√
     Outpatient pharmacy√a√√a√
     Out of pocket√√
    Indirect cost components
     Productivity loss (e.g., days lost from work)√
     Patient time√
     Caregiver time

    Abbreviations: SEER-Medicare, Surveillance Epidemiology and End Results-Medicare; MEPS, Medical Expenditure Panel Survey; H-CUP, Healthcare Cost and Utilization Project; MCBS, Medicare Current Beneficiary Survey; CRN, Cancer Research Network.

    • ↵aData on Medicare part D prescription drug services are available starting in 2006. Before 2006, drugs administered parenterally and their administration was covered by Medicare part B, as were prodrugs, the oral drug equivalent of drugs administered parenterally.

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Cancer Epidemiology Biomarkers & Prevention: 20 (10)
October 2011
Volume 20, Issue 10
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Economic Burden of Cancer in the United States: Estimates, Projections, and Future Research
K. Robin Yabroff, Jennifer Lund, Deanna Kepka and Angela Mariotto
Cancer Epidemiol Biomarkers Prev October 1 2011 (20) (10) 2006-2014; DOI: 10.1158/1055-9965.EPI-11-0650

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Economic Burden of Cancer in the United States: Estimates, Projections, and Future Research
K. Robin Yabroff, Jennifer Lund, Deanna Kepka and Angela Mariotto
Cancer Epidemiol Biomarkers Prev October 1 2011 (20) (10) 2006-2014; DOI: 10.1158/1055-9965.EPI-11-0650
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  • Article
    • Abstract
    • Introduction
    • Temporal Patterns of the Economic Burden of Cancer
    • Estimates and Projections of the National Burden of Cancer
    • Improving Understanding of the Economic Burden of Cancer in the United States
    • Disclosure of Potential Conflicts of Interest
    • Acknowledgments
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  • Dissemination and Translation of Survivorship Research
  • Support for Caregivers of Cancer Patients
  • Quality of Life in Cancer Survivorship Research
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