Article Figures & Data
Figures
- Figure 1.
Perceived response efficacy (confidence that quitting smoking will reduce lung cancer risk) among smokers related to patients with lung cancer before and immediately after receiving genetic test results online.
Tables
- Table 1.
Characteristics of smokers related to patients with lung cancer who took the GSTM1 genetic test and received their results
Variables Whole sample (n = 44) GSTM1 present (lower risk; n = 22) GSTM1 missing (higher risk; n = 22) Difference n % n % n % Gender Male 19 43.2 4 18.2 15 68.2 χ2 = 11.21; df = 1; P = 0.001 Female 25 56.8 18 81.8 7 31.8 Age, y Mean (SD; range, 23-53 y) 40.0 (8.2) 40.8 (8.5) 39.2 (8.0) F = 0.41; df = 1; P = 0.53 Education High school 11 25.0 7 31.8 4 18.2 χ2 = 2.46; df = 2; P = 0.29 Technical/some college 23 52.3 12 54.5 11 50.0 College graduate 10 22.7 3 13.6 7 31.8 Employed full-time Yes 33 75.0 16 72.7 17 77.3 χ2 = 0.12; df = 1; P = 0.73 No 11 25.0 6 27.3 5 22.7 Race/ethnicity White 42 95.5 22 100 20 90.9 χ2 = 2.10; df = 2; P = 0.35 Other (Asian/Irish) 2 4.5 0 0 2 9.1 Relationship to patient Offspring 28 63.6 15 68.2 13 59.1 χ2 = 4.23; df = 3; P = 0.24 Sibling 7 15.9 2 9.1 5 22.7 Aunt/uncle/niece/nephew 5 11.4 4 18.2 1 4.5 Grandchild 4 9.1 1 4.5 3 13.6 Primary caregiver to patient Yes 7 16.3 5 23.8 2 9.1 χ2 = 1.71; df = 1; P = 0.19 No 36 83.7 16 76.2 20 90.9 Frequency of seeing patient Daily 2 4.5 1 4.5 1 4.5 χ2 = 1.27;df = 4; P = 0.87 Weekly 6 13.6 3 13.6 3 13.6 Monthly 9 20.5 4 22.7 4 18.2 Lives with patient 1 2.3 1 4.5 0 0 Other 26 59.1 12 54.5 14 63.6 No. of cigarettes smoked per day Mean (SD; range, 1-30) 16.3 (7.2) 16.2 (7.5) 16.3 (7.0) F = 0.00; df = 1; P = 0.95 Previous use of smoking cessation services/products Yes 24 54.5 11 50.0 13 59.1 χ2 = 0.37; df = 1; P = 0.54 No 20 45.5 11 50.0 9 40.9 - Table 2.
Comprehension and information processing of GSTM1 genetic test results delivered online among smokers related to patients with lung cancer
Outcomes Test result GSTM1-present (lower risk) GSTM1-missing (higher risk) Difference Immediately after receiving genetic test results (online Session 2) Accurate comprehension, n (%) Accurate recall of test result 22 (100) 22 (100) NS Accurate interpretation of test result 12 (55) 22 (100) χ2 = 12.94; df = 1; P < 0.001 Acceptability of test information* Believable 1.23 (0.52) 1.55 (0.60) NS Trustworthy 1.27 (0.55) 1.50 (0.60) NS Easy to understand 1.32 (0.65) 1.45 (0.60) NS Relevant 1.32 (0.65) 1.45 (0.60) NS Important 1.23 (0.53) 1.41 (0.59) NS Processing of genetic test–related information Viewed strengths information page, n (%) 11 (50) 7 (32) NS Viewed weaknesses information page, n (%) 10 (45) 8 (37) NS Total no. of information pages viewed 3.1 (2.6) 2.6 (2.7) NS 6-mo Follow-up Accurate comprehension, n (%) Accurate recall of test result 18 (100) 16 (100) NS Accurate interpretation of test result 10 (56) 15 (94) χ2 = 6.35; df = 1; P = 0.011 Decisional outcomes Regret decision to take genetic test† 0 (0%) 0 (0%) NS Satisfied with decision to take genetic test† 17 (100%) 16 (94%) NS NOTE: Values represent means (SDs) unless otherwise indicated.
Abbreviation: NS, not significant.
↵* Possible scores range from 1 to 7; lower scores indicate more positive and higher acceptability responses (e.g., 1 = believable), and higher scores indicate more negative responses or lower acceptability (e.g., 7 = unbelievable).
↵† Measured using a seven-point scale (1 = strongly disagree, 7 = strongly agree); values shown are proportions who gave responses of 4 to 7, that is, who somewhat to strongly agreed with statement.
Volume 18, Issue 7
