Article Figures & Data
Figures
- Figure 1.
Five-year Kaplan-Meier survival curves for each of the investigated pancreatic histologic subtypes, showing better median overall survival for IPMNs (n = 43) compared with pancreatic endocrine (n = 568), mucinous (n = 880), adenocarcinoma (n = 10,186), and carcinoma not otherwise specified (n = 3,619) tumors (P < 0.0001).
Tables
- Table 1.
Demographic characteristics for pancreatic cancer cases by histologic subtype; incidence cases for 2000 to 2007
Adenocarcinoma (n = 10,186) Mucinous (n = 880) Endocrine (n = 568) IPMN (n = 43) Carcinoma not otherwise specified (n = 3,619) Gender Male 5,155 (50.6) 404 (45.9) 302 (53.2) 21 (48.8) 1,628 (45) Female 5,031 (49.4) 476 (54.1) 266 (46.8) 22 (51.2) 1,991 (55) Age (y) <50 733 (7.2) 76 (8.6) 155 (27.3) 3 (7) 137 (3.8) 50-59 1,813 (17.8) 171 (19.4) 147 (25.9) 8 (18.6) 339 (9.4) 60-69 2,631 (25.8) 218 (24.8) 125 (22) 5 (11.6) 571 (15.8) 70-79 3,199 (31.4) 270 (30.7) 99 (17.4) 16 (37.2) 1,022 (28.2) 80+ 1,810 (17.8) 145 (16.5) 42 (7.4) 11 (25.6) 1,550 (42.8) Ethnicity White 6,515 (64) 562 (63.9) 369 (65) 30 (69.8) 2,375 (65.6) Black 773 (7.6) 78 (8.9) 44 (7.8) 2 (4.7) 322 (8.9) Hispanic 1,797 (17.6) 151 (17.2) 86 (15.1) 1 (2.3) 550 (15.2) Chinese 258 (2.5) 17 (1.9) 11 (1.9) 1 (2.3) 93 (2.6) Non-Chinese Asian 784 (7.7) 67 (7.6) 52 (9.2) 8 (18.6) 258 (7.1) Other 59 (0.6) 5 (0.6) 6 (1.1) 1 (2.3) 21 (0.6) Stage Local* 1,489 (17.9) 137 (18.6) 142 (29.8) 33 (80.5) 531 (24.5) Regional 3,357 (40.3) 240 (32.7) 126 (26.5) 8 (19.5) 629 (29.0) Metastatic 3,472 (41.7) 358 (48.7) 208 (43.7) 0 1,011 (46.6) Number missing 1868 155 92 2 1448 Surgery None 8,907 (87.4) 686 (78) 359 (63.2) 8 (18.6) 3,386 (93.6) Pancreatectomy 1,219 (12) 185 (21) 198 (34.9) 34 (79.1) 65 (1.8) Other surgery 45 (0.4) 9 (1) 9 (1.6) 1 (2.3) 13 (0.4) Radiation No 8,697 (85.5) 751 (85.3) 525 (92.8) 41 (95.4) 3,314 (95.3) Yes 1,475 (14.5) 129 (14.7) 41 (7.2) 2 (4.7) 163 (4.7) Chemotherapy No 5,518 (54.2) 511 (58.1) 349 (61.4) 37 (86.1) 2,809 (77.6) Yes 4,378 (43) 352 (40) 201 (35.4) 6 (14) 576 (15.9) Socioeconomic status Lowest 1,470 (14.4) 129 (14.7) 67 (11.8) 3 (7) 594 (16.4) 2nd Lowest 1,853 (18.2) 167 (19) 89 (15.7) 5 (11.6) 734 (20.3) Middle 2,157 (21.2) 157 (17.8) 115 (20.3) 8 (18.6) 782 (21.6) High 2,279 (22.4) 201 (22.8) 121 (21.3) 10 (23.3) 773 (21.4) Highest 2,427 (23.8) 226 (25.7) 176 (31) 17 (39.5) 736 (20.3) ↵* Includes in situ cases, as described in the text.
- Table 2.
Multivariate survival analysis using Cox proportional hazards model; incidence cases for 2000 to 2007
Histologic subtype HR (95% CI) Adenocarcinoma 1.00 (reference) Mucinous 0.84 (0.77-0.90) Endocrine 0.28 (0.25-0.32) IPMN 0.19 (0.10-0.35) Carcinoma not otherwise specified 1.07 (1.03-1.12) NOTE: Model adjusted for age at diagnosis, gender, ethnicity, stage, surgery, radiation, chemotherapy, and socioeconomic status.
Abbreviation: HR, hazard ratio.
October 2008
Volume 17, Issue 10
Volume 17, Issue 10
A Population-Based, Descriptive Analysis of Malignant Intraductal Papillary Mucinous Neoplasms of the Pancreas
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