Skip to main content
  • AACR Publications
    • Blood Cancer Discovery
    • Cancer Discovery
    • Cancer Epidemiology, Biomarkers & Prevention
    • Cancer Immunology Research
    • Cancer Prevention Research
    • Cancer Research
    • Clinical Cancer Research
    • Molecular Cancer Research
    • Molecular Cancer Therapeutics

AACR logo

  • Register
  • Log in
  • My Cart
Advertisement

Main menu

  • Home
  • About
    • The Journal
    • AACR Journals
    • Subscriptions
    • Permissions and Reprints
  • Articles
    • OnlineFirst
    • Current Issue
    • Past Issues
    • CEBP Focus Archive
    • Meeting Abstracts
    • Progress and Priorities
    • Collections
      • COVID-19 & Cancer Resource Center
      • Disparities Collection
      • Editors' Picks
      • "Best of" Collection
  • For Authors
    • Information for Authors
    • Author Services
    • Best of: Author Profiles
    • Informing Public Health Policy
    • Submit
  • Alerts
    • Table of Contents
    • Editors' Picks
    • OnlineFirst
    • Citation
    • Author/Keyword
    • RSS Feeds
    • My Alert Summary & Preferences
  • News
    • Cancer Discovery News
  • COVID-19
  • Webinars
  • Search More

    Advanced Search

  • AACR Publications
    • Blood Cancer Discovery
    • Cancer Discovery
    • Cancer Epidemiology, Biomarkers & Prevention
    • Cancer Immunology Research
    • Cancer Prevention Research
    • Cancer Research
    • Clinical Cancer Research
    • Molecular Cancer Research
    • Molecular Cancer Therapeutics

User menu

  • Register
  • Log in
  • My Cart

Search

  • Advanced search
Cancer Epidemiology, Biomarkers & Prevention
Cancer Epidemiology, Biomarkers & Prevention
  • Home
  • About
    • The Journal
    • AACR Journals
    • Subscriptions
    • Permissions and Reprints
  • Articles
    • OnlineFirst
    • Current Issue
    • Past Issues
    • CEBP Focus Archive
    • Meeting Abstracts
    • Progress and Priorities
    • Collections
      • COVID-19 & Cancer Resource Center
      • Disparities Collection
      • Editors' Picks
      • "Best of" Collection
  • For Authors
    • Information for Authors
    • Author Services
    • Best of: Author Profiles
    • Informing Public Health Policy
    • Submit
  • Alerts
    • Table of Contents
    • Editors' Picks
    • OnlineFirst
    • Citation
    • Author/Keyword
    • RSS Feeds
    • My Alert Summary & Preferences
  • News
    • Cancer Discovery News
  • COVID-19
  • Webinars
  • Search More

    Advanced Search

Letters to the Editor

Effect of Soy Protein on Testosterone Levels

Mark Messina, Jill Hamilton-Reeves, Mindy Kurzer and William Phipps
Mark Messina
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Jill Hamilton-Reeves
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Mindy Kurzer
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
William Phipps
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
DOI: 10.1158/1055-9965.EPI-07-2543 Published December 2007
  • Article
  • Info & Metrics
  • PDF
Loading

To the Editors: Goodin et al. (1) reported a 19% decrease in mean serum testosterone levels among 12 men over a 4-week period in response to the daily consumption of 56 g isolated soy protein. These data are inconsistent with the results of a meta-analysis recently completed by the authors of this letter. This inconsistency, as judged by Fig. 1 in the paper by Goodin et al. (1), may stem largely from the change that occurred in just one subject (SP #2). In this regard, we would ask Goodin et al. (1) to consider reanalyzing the results (or providing the data so that we may do so) excluding this subject, who clearly appears to be an outlier. His baseline testosterone level was more than twice that of any other subject and ∼50% greater than the normal reference range as stated in the paper. Additionally, this subject experienced an ∼40% decrease in testosterone within just 4 weeks and a further 30% or so decrease during the 2-week post-soy consumption period, whereas the mean value for all other subjects increased during this 2-week period. Parenthetically, we are interested in knowing whether Goodin et al. (1) are able to offer a possible explanation for such an elevated baseline level. In addition, for the record, we would ask that Goodin et al. (1) list the correct values for testosterone and luteinizing hormone levels, as the data listed in the text do not match the data in the figures.

As well, it would be helpful if Goodin et al. (1) could provide additional details about the study so we have a better understanding of the experimental design. Specifically, the isoflavone content of the soy product used would be of interest, as would details about the assays used.

References

  1. ↵
    Goodin S, Shen F, Shih WJ, et al. Clinical and biological activity of soy protein powder supplementation in healthy male volunteers. Cancer Epidemiol Biomarkers Prev 2007;16:829–33.
    OpenUrlAbstract/FREE Full Text
PreviousNext
Back to top
Cancer Epidemiology Biomarkers & Prevention: 16 (12)
December 2007
Volume 16, Issue 12
  • Table of Contents
  • Table of Contents (PDF)

Sign up for alerts

View this article with LENS

Open full page PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for sharing this Cancer Epidemiology, Biomarkers & Prevention article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Enter multiple addresses on separate lines or separate them with commas.
Effect of Soy Protein on Testosterone Levels
(Your Name) has forwarded a page to you from Cancer Epidemiology, Biomarkers & Prevention
(Your Name) thought you would be interested in this article in Cancer Epidemiology, Biomarkers & Prevention.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
Effect of Soy Protein on Testosterone Levels
Mark Messina, Jill Hamilton-Reeves, Mindy Kurzer and William Phipps
Cancer Epidemiol Biomarkers Prev December 1 2007 (16) (12) 2795; DOI: 10.1158/1055-9965.EPI-07-2543

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
Effect of Soy Protein on Testosterone Levels
Mark Messina, Jill Hamilton-Reeves, Mindy Kurzer and William Phipps
Cancer Epidemiol Biomarkers Prev December 1 2007 (16) (12) 2795; DOI: 10.1158/1055-9965.EPI-07-2543
del.icio.us logo Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • References
  • Info & Metrics
  • PDF
Advertisement

Related Articles

Cited By...

More in this TOC Section

  • Copy Number Variation and Ovarian Cancer Risk—Letter
  • Genome-wide Analysis of Common Copy Number Variation and Epithelial Ovarian Cancer Risk—Response
  • Shift Work, Chronotype, and Cancer Risk—Response
Show more Letters to the Editor
  • Home
  • Alerts
  • Feedback
  • Privacy Policy
Facebook   Twitter   LinkedIn   YouTube   RSS

Articles

  • Online First
  • Current Issue
  • Past Issues

Info for

  • Authors
  • Subscribers
  • Advertisers
  • Librarians

About Cancer Epidemiology, Biomarkers & Prevention

  • About the Journal
  • Editorial Board
  • Permissions
  • Submit a Manuscript
AACR logo

Copyright © 2021 by the American Association for Cancer Research.

Cancer Epidemiology, Biomarkers & Prevention
eISSN: 1538-7755
ISSN: 1055-9965

Advertisement