Table 3.
Table 3.
Association between CYP11α variants and prostate cancer, in the entire family-based study sample, stratified by disease aggressiveness
| CYP11α | Entire sample | Low aggressive* | High aggressive† | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Cases/controls | OR (95% CI)‡ | P | Cases/controls | OR (95% CI)‡ | P | Cases/controls | OR (95% CI)‡ | P | |
| (tttta)n§ | |||||||||
| None | 85 of 90 | 1.00 | 40 of 42 | 1.00 | 38 of 43 | 1.00 | |||
| One copy | 199 of 218 | 0.86 (0.53-1.38) | 0.52 | 87 of 92 | 0.72 (0.33-1.59) | 0.42 | 100 of 107 | 1.11 (0.59-2.11) | 0.75 |
| Two copies | 153 of 170 | 0.84 (0.47-1.48) | 0.54 | 60 of 73 | 0.59 (0.24-1.45) | 0.25 | 86 of 89 | 1.21 (0.55-2.67) | 0.64 |
January 2021
Volume 30, Issue 1
Volume 30, Issue 1
