Body Mass Index in Relation to Ovarian Cancer Survival

DOI: 10.1158/1055-9965.EPI-04-0519 Published May 2005

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Figure 1.
Survival curves by BMI at 5 years before diagnosis.

Table 1.

Selected characteristics of ovarian cancer patients by survival status (n = 207)

Selected characteristics	Alive (n = 113), n (%)	Dead (n = 94), n (%)
Age at diagnosis (y), mean (SD)*	46.7 (12.7)	51.6 (8.8)
<40	34 (30.1)	7 (7.4)
40-49	33 (29.2)	39 (41.5)
50-59	27 (23.9)	29 (30.9)
≥60	19 (16.8)	19 (20.2)
Body height (cm), mean (SD)	158.2 (4.9)	158.1 (5.1)
Body weight (kg), mean (SD)
At diagnosis	55.5 (7.9)	56.9 (8.7)
5 y ago*	54.8 (7.8)	58.2 (7.7)
At age 21 y^†	51.7 (6.6)	53.3 (6.4)
Body mass index (kg/m²), mean (SD)
At diagnosis	22.2 (2.9)	22.7 (3.1)
5 y ago*	21.9 (2.7)	23.3 (2.7)
At age 21 y^†	20.7 (2.4)	21.3 (2.3)
Tobacco smoking
Never	111 (98.2)	92 (97.9)
Ever	2 (1.8)	2 (2.1)
Alcohol consumption
Never	79 (69.9)	58 (61.7)
Ever	34 (30.1)	36 (38.3)
Menopausal status
Premenopause	74 (65.5)	50 (53.2)
Postmenopause	39 (34.5)	44 (46.8)
Hormone replacement therapy
Never	110 (97.3)	93 (98.9)
Ever	3 (2.7)	1 (1.1)
Oral contraceptive use
Never	88 (77.9)	72 (76.6)
Ever	25 (22.1)	22 (23.4)
Ovarian cancer in first-degree relatives
No	110 (97.3)	91 (96.8)
Yes	3 (2.7)	3 (3.2)
Fesddration Internationale des Gynaecologistes et Obstetristes stage*
I	62 (54.9)	3 (3.2)
II	14 (12.4)	1 (1.1)
III	35 (30.9)	78 (82.9)
IV	2 (1.8)	12 (12.8)
Histopathologic grade*
Well differentiated	43 (38.1)	4 (4.2)
Moderately differentiated	16 (14.2)	20 (21.3)
Poorly differentiated	30 (26.5)	61 (64.9)
Not available	24 (21.2)	9 (9.6)
Ascites*
No	53 (46.9)	2 (2.1)
Yes	60 (53.1)	92 (97.9)
Residual lesions* (cm)
<2	100 (88.5)	22 (23.4)
≥2	13 (11.5)	72 (76.6)
Chemotherapy
No	3 (2.7)	4 (4.3)
Yes	110 (97.3)	90 (95.7)

NOTE: Differences between alive and dead patients were assessed using a χ² test for categorical variables and a t test for continuous variables.
↵* P < 0.01.
↵† P < 0.05.

Table 2.

Crude and adjusted HRs of epithelial ovarian cancer death according to anthropometric variables (n = 207)

NOTE: Estimates from Cox regression models included terms for age at diagnosis (in y, continuous), total energy intake (kcal, continuous), menopausal status (premenopause and postmenopause), Fesddration Internationale des Gynaecologistes et Obstetristes stage (I, II, III, and IV), histopathologic grade of differentiation (well, moderately, poorly differentiated, and not available), ascites (no/yes), residual lesions (<2 and ≥2 cm), and chemotherapy (no/yes).
↵* Quantity of anthropometric variables was tested for linear trend.