Table 1.

Case–control cohort baseline characteristics

CharacteristicCases, n (%) n = 266Controls, n (%) n = 156
Age (years)
 Mean (±SD)62.69 (±11.79)46.10 (±16.34)
 Median (range)63 (33–92)45 (20–79)
Ethnicity
 White-American190 (71.43)111 (71.15)
 African-American76 (28.57)45 (28.85)
Molecular subtype
 Lum A174 (65.41)
 Lum B25 (9.40)
 HER2+37 (13.91)
 Basal-like25 (9.40)
 HR+5 (1.88)
Clinical stage
 I183 (68.80)
 II62 (23.31)
 III10 (3.76)
 IV5 (1.88)
 Other5 (1.88)
 Not available1 (0.37)
DARC/ACKR1 Genotype (rs2814778)
 AA157 (73.71)110 (73.33)
 AG23 (10.80)15 (10.00)
 GG33 (15.49)25 (16.67)
DARC/ACKR1 RBC Phenotype
 Positive145 (69.05)42 (89.36)
 Intermediate41 (19.52)3 (6.38)
 Negative24 (11.43)2 (4.26)
  • Abbreviations: HR, hormone receptor; Lum A, Luminal A; Lum B, Luminal B; RBC, red blood cell.