Table 2.

Demographic and clinical factors in study cohort

VariableOverall cohortStudy 1 “Specificity”Study 2 “Cutoff”Study 3 “DeeP-C”P
Patients, n1,050485228337
Median age (IQR), years65.6 (56.8–72.3)64.1 (56.6–71.8)62.4 (53.0–70.9)68.5 (65.0–73.8)< 0.0001
Women, n (%)563 (54)257 (53)119 (52)187 (55)0.70
White race, n (%)981 (93)437 (90)216 (95)328 (97)< 0.0001
Patient status by specificity cutoff
Per-protocol (90%)
 FP, n (%)160 (15)65 (13)36 (16)59 (18)0.27
 TN, n (%)890 (85)420 (87)192 (84)278 (82)
Calibrated (90%)
 FP, n (%)113 (11)53 (11)25 (11)35 (10)1.00
 TN, n (%)937 (89)432 (89)203 (89)302 (90)
Calibrated (95%)
 FP, n (%)51 (5)25 (5)10 (4)16 (5)0.93
 TN, n (%)999 (95)460 (95)218 (96)321 (95)