Table 3.

HRs, calibrated and age adjusted

5-year cumulativeHR (95% CI) for FP MT-sDNAa
Outcomeincidence % (95% CI)Per-protocol cutoffsCalibrated 90th percentileCalibrated 95th percentile
All-cause mortality3 (2–4)0.9 (0.4–2.7)1.7 (0.6–4.5)2.3 (0.7–7.6)
Subsequent aerodigestive cancerb1 (0.3–2)1.3 (0.3–6.7)4.1 (1.0–17.6)5.5 (1.1–27.5)
Any subsequent cancerc5 (4–7)1.1 (0.6–2.3)0.8 (0.3–2.1)1.1 (0.4–3.7)
Any subsequent alarm signs13 (10–17)0.8 (0.4–1.5)0.6 (0.3–1.4)0.6 (0.2–2.1)
  • aAge adjusted.

  • bIncluded 1 colorectal, 3 pancreatic, 3 lung, and 1 bile duct.

  • cAbove plus 16 skin, 12 genitourinary, 8 breast, 2 hematologic, 1 ophthalmologic, and 1 glioblastoma.