Table 4.

Associations between statin use and prostate cancer aggressiveness, stratified by prostate cancer screening frequency

n, cases (aggressive)ORa (95% CI)ORb (95% CI)
Never screened
 Statin nonusers278 (87)1.00 (ref)1.00 (ref)
 Statin users82 (23)0.81 (0.47–1.41)0.79 (0.45–1.39)
≤ 1 Screening tests per year
 Statin nonusers365 (61)1.00 (ref)1.00 (ref)
 Statin users260 (35)0.67 (0.42–1.07)0.66 (0.41–1.06)
> 1 Screening tests per year
 Statin nonusers562 (85)1.00 (ref)1.00 (ref)
 Statin users383 (53)0.79 (0.54–1.15)0.78 (0.53–1.15)
  • aAdjusted for age only.

  • bAdjusted for age, race, site, BMI, cholesterol intake, percent saturated fat intake, and smoking status.