Table 5.

SSB intake and type I endometrial cancer risk, stratified by BMI, physical activity level, comorbid diabetes, and cigarette smoking

SSB intakea
<1 serving/week (reference)≥1 serving/week
CasesPerson-yearsCasesCasesHR (95% CI)bPinteraction
BMI (kg/m2)
 <25135180,18094411.17 (0.80–1.70)0.18
 25–<30139159,83593461.09 (0.75–1.58)
 ≥3023292,807138941.38 (1.05–1.82)
Physical activity level
 Low236197,904142941.33 (1.01–1.74)0.99
 Medium131119,05592391.04 (0.71–1.53)
 High131109,34488431.44 (0.99–2.09)
Diabetes
 No458411,3682851731.29 (1.06–1.56)0.77
 Yes4721,1604071.14 (0.50–2.56)
Cigarette smoking
 Never37159,0582331381.21 (0.97–1.50)0.79
 Past9280,23661311.72 (1.10–2.68)
 Current36288,17526100.99 (0.47–2.07)
  • aAdjusted for total energy intake using nutrient residual methods.

  • bCompared with type I endometrial cancer risk in women reporting <1 serving/week SSB intake as a reference group in each stratified category. Adjusted for age, BMI, smoking (never, past, and current), physical activity (low, medium, or high), alcohol use (none, <4 g/day, or ≥4 g/day), estrogen use (never, ever), age at menarche (≤12 or >12 years), age at menopause (<50 or ≥50 years), number of live births, history of diabetes, and coffee intake, except for the variable for stratification.