Table 2

Comparisons of GSTM1 and GSTT1 genotypes in cases and controls

Risk factorControlsCasesOR (95% CI)
UnadjustedAdjusteda
GSTM1-0 110 (47.6%)110 (46.6%)1.0b1.0b
GSTM1-1 121 (52.4%)126 (53.4%)1.04 (0.72–1.50)1.07 (0.74–1.55)
GSTT1-0 72 (31.2%)46 (19.8%)1.0b1.0b
GSTT1-1 159 (68.8%)186 (80.2%)1.83 (1.20–2.80)1.83 (1.19–2.80)
GST-0 c 31 (13.3%)22 (9.3%)1.0b1.0b
GST-1 202 (86.7%)214 (90.7%)1.49 (0.84–2.66)1.53 (0.85–2.73)
GST1-0 d 151 (65.9%)134 (57.8%)1.0b1.0b
GST1-1 78 (34.1%)98 (42.2%)1.42 (0.97–2.07)1.46 (1.00–2.14)
  • a OR adjusted by multiple logistic regression for age and race.

  • b Reference group.

  • c GST-0 is defined as GSTM1-0 and GSTT1-0; GST-1 is defined as GSTM1-1 or GSTT1-1.

  • d GST1-0 is defined as GSTM1-0 or GSTT1-0; GST1-1 is defined as GSTM1-1 and GSTT1-1.