Table 3.

Significant results from individual SNP effects on ALL

GeneSNPGenotypeHispanicsWhites
Control/caseOR (95% CI)aPunadjOR (95% CI)bPadjControl/caseOR (95% CI)a
MLLrs525549TT98/27Ref-83/49Ref- 
AA13/123.35 (1.37–8.18)0.0082.84 (1.07–7.55)0.03641/170.70 (0.36–1.37)0.299 
AT64/261.47 (0.79–2.75)0.2221.24 (0.62–2.46)0.540115/670.99 (0.62–1.57)0.955 
AA vs. AT/TT13/122.82 (1.21–6.56)0.0162.56 (1.02–6.41)0.04441/170.71 (0.38–1.30)0.267 
MLLrs6589664AA46/16RefGG112/66Ref- 
GG31/252.32 (1.07–5.03)0.0341.85 (0.76–4.47)0.174AA30/70.40 (0.16–0.95)0.038 
AG98/240.70 (0.34–1.45)0.3420.65 (0.29–1.44)0.286AG97/601.05 (0.67–1.63)0.830 
GG vs. AG/AA31/252.90 (1.54–5.47)0.0012.49 (1.23–5.04)0.011AA vs. AG/GG30/70.39 (0.17–0.91)0.029 
EP300rs5758222AA126/32Ref-99/56Ref- 
GG5/43.15 (0.80–12.4)0.1013.11 (0.74–13.15)0.12325/130.92 (0.44–1.94)0.825 
AG44/282.51 (1.36–4.62)0.0032.75 (1.41–5.35)0.003113/600.94 (0.60–1.48)0.784 
GG/AG vs. AA49/322.57 (1.42–4.64)0.0022.79 (1.46–5.32)0.002138/730.94 (0.61–1.44)0.762 
EP300rs7286979GG126/33Ref-97/56Ref- 
AA6/42.55 (0.68–9.55)0.1662.58 (0.65–10.31)0.18026/120.80 (0.37–1.71)0.563 
AG43/282.49 (1.35–4.58)0.0032.68 (1.38–5.21)0.004115/660.99 (0.64–1.55)0.979 
AA/AG vs. GG49/322.49 (1.39–4.49)0.0022.67 (1.40–5.07)0.003141/780.96 (0.62–1.47)0.846 
EP300rs20551GG69/14RefAA120/63Ref- 
AA28/142.46 (1.04–5.83)0.0402.86 (1.06–7.73)0.039GG21/121.09 (0.50–2.36)0.830 
AG78/362.27 (1.13–4.57)0.0212.77 (1.22–6.29)0.015AG97/521.02 (0.65–1.61)0.928 
AA/AG vs. GG106/502.32 (1.19–4.52)0.0132.79 (1.26–6.18)0.011GG/AG vs. AA118/641.03 (0.67–1.59)0.882 

NOTE: All significant values are in bold.

  • aUnadjusted and

  • bAdjusted Native American ancestry.