Table 4.

Sensitivity, specificity, PPV, and NPV of all terminal nodes for the race-specific final pruned CART models

Race/ethnicityCART pathSensitivitySpecificityPPVNPV
European AmericansCYP3A43 genotype10999439
CYP3A43 genotype* family history of prostate cancer22907943
CYP3A43 genotype* family history of prostate cancer* age at consent86336859
CYP3A43 genotype* family history of prostate cancer* age at consent* history of BPH10998757
African AmericansFamily history of prostate cancer28854276
Family history of prostate cancer* European ancestry* AR GGC repeats27906467
Family history of prostate cancer* European ancestry* CYP3A4/CYP3A5 haplotype82596777

NOTE: All the values are expressed as percentages.