Table 2.

Individual group differences in the LI (immunohistochemistry) and log 2 ratios (qPCR) of IGFBP-2, -3, and -5

VariablesNormalDAAAGBMKruskal-Wallis test
χ2; PPost hoc P*
IGFBP-2 LI0.0000 ± 0.0000 (0.0000)0.0000 ± 0.0000 (0.0000)2.500 ± 8.756 (0.0000)30.070 ± 17.150 (30.000)81.92; <0.0001<0.05
<0.05
<0.05§
IGFBP-2 log 2 ratio0.0000 ± 0.935 (−0.116)0.816 ± 1.195 (0.789)1.210 ± 1.606 (1.100)4.602 ± 1.724 (4.815)125.30; <0.0001<0.05
<0.05
<0.05§
IGFBP-3 LI0.0000 ± 0.0000 (0.0000)6.333 ± 10.93 (0.0000)12.500 ± 13.780 (10.000)34.240 ± 17.020 (35.000)73.53; <0.0001<0.05
<0.05
<0.05§
IGFBP-3 log 2 ratio0.0000 ± 1.017 (0.123)−0.624 ± 2.105 (−0.386)0.866 ± 2.343 (0.819)3.542 ± 2.123 (3.462)89.00; <0.0001<0.05
<0.05
<0.05§
IGFBP-5 LI0.0000 ± 0.0000 (0.0000)6.000 ± 10.390 (0.0000)7.500 ± 10.000 (0.0000)24.820 ± 13.680 (25.000)64.09; <0.0001<0.05
<0.05
<0.05§
IGFBP-5 log 2 ratio0.0000 ± 1.038 (0.128)1.039 ± 1.634 (1.621)0.425 ± 1.818 (0.814)1.844 ± 2.077 (1.909)36.05; <0.0001<0.05
>0.05
<0.05§

NOTE: Values in parentheses are the median.

  • *Dunn's post hoc P value.

  • Normal vs. GBM.

  • DA vs. GBM.

  • §AA vs. GBM.