Table 2.

ORs and corresponding 95% CIs of gastric, pancreatic, and endometrial cancers, according to ever consumption of low-calorie sweeteners in strata of selected covariates

CovariatesLow-calorie sweeteners (ever vs never users), OR* (95% CI)
Gastric cancerPancreatic cancerEndometrial cancer
Sex
    Males0.76 (0.32-1.79)0.66 (0.31-1.38)
    Females0.93 (0.39-2.18)0.62 (0.29-1.34)
Age (y)
    <600.32 (0.08-1.22)0.99 (0.39-2.49)0.84 (0.49-1.44)
    ≥601.12 (0.57-2.21)0.47 (0.24-0.91)1.14 (0.68-1.91)
Education (y)
    <70.58 (0.22-1.51)0.52 (0.23-1.19)1.16 (0.69-1.93)
    ≥71.06 (0.50-2.26)0.68 (0.34-1.36)0.82 (0.47-1.43)
BMI (kg/m2)
    <250.49 (0.18-1.32)0.62 (0.23-1.67)1.03 (0.47-2.25)
    ≥251.13 (0.54-2.37)0.72 (0.39-1.34)1.03 (0.67-1.57)
Total energy intake (calories)
    <21000.63 (0.29-1.37)0.69 (0.28-1.66)1.07 (0.66-1.73)
    ≥21001.19 (0.47-3.01)0.47 (0.24-0.92)0.75 (0.40-1.38)
History of diabetes
    No0.71 (0.36-1.38)0.59 (0.32-1.09)1.03 (0.69-1.54)
    Yes1.37 (0.34-5.55)0.95 (0.38-2.36)0.69 (0.24-1.95)
Smoking status
    Never smokers0.56 (0.20-1.53)0.91 (0.42-1.99)1.01 (0.64-1.57)
    Current/ex-smokers1.09 (0.52-2.28)0.53 (0.26-1.05)0.98 (0.49-1.96)
Hot beverages (cups/week)
    <170.72 (0.27-1.91)0.53 (0.24-1.13)1.17 (0.68-2.02)
    ≥170.98 (0.47-2.06)0.81 (0.38-1.69)0.86 (0.51-1.44)
  • *Estimated by unconditional multiple logistic regression models adjusted for age, sex (when appropriate), study center (when appropriate), year of interview, education, BMI, tobacco smoking, history of diabetes, consumption of hot beverages, and total energy intake.

  • Estimated by unconditional multiple logistic regression models adjusted for age, sex (when appropriate), study center (when appropriate), and year of interview.