Table 4.

RR (95% CI) of BCC and SCC by group of serum selenium concentration at baseline in 485 participants of the Nambour Skin Cancer Study, 1996-2004

Selenium concentration
Ptrend
Group 1Group 2Group 3
Median (μmol/L*; min-max)0.9 (0.4-1.0)1.1 (1.1-1.2)1.4 (1.3-2.8)
BCC: person-based
    No. persons affected/total participants33/19428/16316/128
    Basic RR (95% CI)1.001.02 (0.61-1.69)0.67 (0.37-1.22)0.19
    Multivariate RR (95% CI)1.000.97 (0.58-1.61)0.58 (0.32-1.07)0.08
BCC: tumor-based
    No. tumors/total participants20/16322/15917/163
    Basic RR (95% CI)1.001.09 (0.56-2.10)0.57 (0.28-1.17)0.14
    Multivariate RR (95% CI)1.001.02 (0.56-1.87)0.43 (0.21-0.86)0.02
SCC: person-based
    No. persons affected/total participants27/19421/16311/128
    Basic RR (95% CI)1.000.92 (0.52-1.63)0.54 (0.27-1.08)0.08
    Multivariate RR (95% CI)1.000.89 (0.49-1.60)0.49 (0.24-0.99)0.05
SCC: tumor-based
    No. tumors/total participants17/16221/15821/165
    Basic RR (95% CI)1.000.97 (0.48-1.95)0.44 (0.19-1.00)0.06
    Multivariate RR (95% CI)1.000.86 (0.44-1.67)0.36 (0.15-0.82)0.02
  • * 1 μmol/L ≈ 79 μg/L.

  • Adjusted for age and sex. RRs from Poisson regression (person-based) or negative binomial regression (tumor-based).

  • Adjusted for age, sex, pack-years of smoking, alcohol intake (continuous), time spent outdoors on weekdays, and history of skin cancer before 1996.