Table 1.

Twenty-three colorectal cancer versus normal tissue expression profiling studies included in analysis

ReferencePlatformNo. genes/featuresUp-regulated features (Mapped)Down-regulated features (Mapped)
Habermann et al. (6)Hs-UniGEM2 human cDNA microarray9,12824 (23)34 (29)
Lin et al. (8)Custom cDNA microarray23,04063 (53)375 (321)
Buckhaults et al. (19)SAGEN/A153 (106)246 (201)
Notterman et al. (17)Affymetrix Human 6500 GeneChip Set7,45719 (19)47 (45)
Galamb et al. (45)Human Atlas Glass 1.0 cDNA microarray1,09083 (83)17 (17)
Wang et al. (46)TGS s-4k cDNA microarray3,80023 (23)0
Croner et al. (20)Affymetrix HG-U133A22,28367 (66)63 (62)
Kwon et al. (47)Macrogen MAGIC cDNA microarray4,60877 (77)45 (44)
Bertucci et al. (48)Custom nylon cDNA microarray8,074125 (125)109 (109)
Ohmachi et al. (49)Agilent cDNA microarray12,81484 (82)0
Mori et al. (50)Human Atlas Glass 1.0 cDNA microarray1,09032 (32)0
Kim et al. (22)Oligonucleotide microarray from Compugen/Sigma-Genosys18,861272 (271)216 (216)
Zou et al. (18)Custom cDNA microarray8,00088 (69)142 (118)
Koehler et al. (51)Atlas Human Cancer 1.2 Array1,18531 (29)14 (13)
Ichikawa et al. (52)Custom cDNA microarray20,78447 (45)83 (78)
Jansova et al. (53)Human 19K microarrays (Clinical Genomic Centre)19,20131 (29)163 (162)
Grade et al. (54)National Cancer Institute oligonucleotide arrays (Operon V2 oligo set)21,5431,057 (994)36 (36)
Bianchini et al. (55)Human 19K microarrays (Clinical Genomic Centre)19,20176 (76)12 (12)
Agrawal et al. (21)Affymetrix Human 6800 GeneChip Set7,129257 (253)82 (78)
Sugiyama et al. (56)Human Cancer Pathway Finder Gene Arrays (Superarray Bioscience)9613 (13)11 (11)
Kitahara et al. (57)Custom cDNA microarray9,21644 (42)191 (163)
Williams et al. (58)Custom cDNA microarray9,592203 (192)85 (76)
Takemasa et al. (59)Custom cDNA microarray4,60822 (22)36 (36)
Total3,582 (3,273)2,955 (2,613)