Table 2.

Relationship between a history of migraine and risks of invasive ductal and invasive lobular breast carcinomas

Controls (n = 1,474)
Ductal carcinoma (n = 1,199)
Lobular carcinoma (n = 739)
n (%)n (%)OR* (95% CI)n (%)OR* (95% CI)
Never diagnosed with migraine1,202 (82)1,037 (87)1.00 (reference)630 (85)1.00 (reference)
Ever diagnosed with migraine272 (19)162 (14)0.67 (0.54-0.82)109 (15)0.68 (0.52-0.90)
Age at migraine diagnosis (y)
    <2073 (5)32 (3)0.50 (0.33-0.76)23 (3)0.55 (0.33-0.91)
    20-39110 (8)80 (7)0.83 (0.62-1.13)48 (7)0.77 (0.53-1.12)
    ≥4089 (6)50 (4)0.62 (0.43-0.89)36 (5)0.62 (0.41-0.95)
    P value for difference across age categories0.520.85
Ever use of prescription migraine medications
    No127 (9)67 (6)0.58 (0.43-0.79)53 (7)0.65 (0.46-0.93)
    Yes144 (10)92 (8)0.73 (0.56-0.97)55 (8)0.69 (0.49-0.97)
P value for difference across medication categories0.250.98
  • * ORs adjusted for age and reference year.

  • P < 0.05.