Table 1.

Description of the study population, by colon and rectal anatomic site groupings

VariableColon
Rectum
CasesMatched controlsP difference* tests.CasesMatched controlsP difference*
n644644382382
    Male subjects, %53.153.157.357.3
    Nonfasting subjects, %72.772.780.180.1
Mean age, y (5th-95th percentile)
    At recruitment59.1 (46.1-71.6)59.1 (46.2-71.6)0.2958.2 (47.7-69.7)58.2 (47.7-69.5)0.87
    At blood donation59.2 (46.1-71.6)59.2 (46.2-71.7)0.3258.3 (47.7-69.7)58.3 (48.0-69.7)0.96
    At diagnosis62.2 (50.0-75.0)61.4 (50.0-73.0)
Mean y of follow-up3.5 (0.3-7.0)3.6 (0.6-7.3)
Mean BMI (5th-95th percentile)27.3 (21.2-34.9)26.9 (21.1-33.7)0.0827.0 (21.2-33.9)26.6 (21.5-32.5)0.10
Mean waist circumference92.6 (71.0-114.0)90.7 (71.0-110.5)0.00191.9 (72.0-111.0)90.7 (69.00-110.0)0.10
Mean WHR (5th-95th percentile)0.89 (0.73-1.03)0.88 (0.73-1.03)0.020.90 (0.73-1.05)0.89 (0.72-1.04)0.15
Alcohol intake, g/d17.6 (0-62.3)16.4 (0-60.7)0.5122.1 (0.003-75.5)17.5 (0.002-60.5)0.004
Past use of hormone therapy, %
    Yes19.215.60.1911.017.80.08
Smoking status, %0.430.81
    Never40.544.437.235.9
    Former35.933.733.035.9
    Smoker23.021.629.328.0
Physical activity, %§0.160.15
    Inactive16.613.016.213.9
    Moderately inactive29.227.028.525.1
    Moderately active43.848.343.244.0
    Active9.511.011.514.9
Geometric mean (5th-95th percentile)
    HbA1c, %5.8 (5.2-7.1)5.7 (5.1-6.6)5.8 (5.1-7.5)5.8 (5.1-6.8)
Diabetic subjects from questionnaires, %5.03.96.54.2
Diabetic subjects HbA1c>6.5,%9.96.511.58.9
Diabetic subjects from questionnaires or HbA1c>6.5, %11.57.613.110.0
  • * P values for differences in means between cases and controls determined by paired t tests, for smoking status and physical activity P values were determined by paired χ2 tests.

  • In women only.

  • Smoking status of the remaining subjects is missing.

  • § Physical activity status of the remaining subjects is missing.

  • Mean/median and 5th-95th percentile values refer to the non-logarithmically transformed distribution.