Table 3.

Analysis of 10 haplogroups in PC cases and controls

HaplogroupTesting set
Validation set
Combined set
Controls (N = 615)Cases (N = 474)OR* (95% CI)Controls (N = 487)Cases (N = 481)OR* (95% CI)Controls (N = 1,102)Cases (N = 955)OR* (95% CI)
H2101971 (–)2061911 (–)4163881 (–)
I12100.888 (0.375-2.102)1390.747 (0.312-1.787)25190.815 (0.442-1.503)
J51400.836 (0.529-1.321)49430.946 (0.601-1.491)100830.890 (0.645-1.228)
K40310.826 (0.497-1.373)31331.148 (0.677-1.947)71640.966 (0.671-1.392)
T54390.770 (0.488-1.214)444160.858 (0.528-1.394)98740.810 (0.581-1.128)
U95640.718 (0.495-1.042)77700.980 (0.671-1.432)1721340.835 (0.641-1.089)
V23180.834 (0.437-1.593)18201.198 (0.615-2.334)41380.994 (0.626-1.578)
W850.666 (0.214-2.071)970.839 (0.306-2.297)17120.757 (0.357-1.605)
X1080.853 (0.330-2.205)620.360 (0.072-1.803)16100.670 (0.300-1.494)
Com22241.163 (0.632-2.141)16322.157 (1.147-4.057)38561.580 (1.023-2.440)
  • * ORs were estimated prior to statistical adjustment for covariates (age, gender, and smoking history).

  • A composite group of two less frequent haplogroups.