Table 2.

Analysis of 24 mtSNPs in patients with PC and controls

Position and variantLocationAccession no., if knownTesting set
Validation set
Combined set
Control (N = 615)PC case (N = 474)P*Control (N = 487)PC case (N = 481)P*Control (N = 1,102)PC case (N = 955)P*
73G/AD-loop338/248255/2120.32258/222248/2290.59596/470503/4410.24
152T/CD-loop427/102358/950.51364/112358/1050.76791/214716/2000.77
489C/TD-loop59/51952/4070.5643/42448/4120.53102/943100/8190.41
709A/G12S rRNA88/48321/1260.7368/41761/4170.57156/900825/430.35
1189C/T12S rRNA44/54133/4310.8032/45535/4410.6376/99668/8720.90
1719A/G16S rRNA34/56028/4420.8726/46015/4650.0960/1,02043/9070.29
3010G/A16S rRNA401/119321/1270.05365/121363/1140.72766/240684/2410.26
4580A/GND224/55819/4510.9518/46720/4600.7242/1,02539/9110.85
7028T/CCOIrs2015062356/223265/2030.11275/210271/2060.97631/433536/4090.24
8251A/GCOIIrs302108931/56721/4500.5826/45521/4380.5657/1,02242/8880.43
9055G/AATPase 6535/56426/430.86438/48430/470.99973/104856/900.91
10398G/AND3rs2853826118/46495/3650.8898/38597/3740.91216/849192/7390.85
11719A/GND4rs2853495322/239234/2330.02248/232231/2440.35570/471465/4770.016
11812G/AND4rs1682240646/53933/4330.6333/45321/4560.1179/99254/8890.14
12308G/AtRNArs2853498148/43799/3650.13109/376109/3690.90257/813208/7340.30
12372A/GND5rs2853499151/429103/3680.12112/372111/3691.00263/801214/7370.24
12705T/CND5rs285412247/54137/4320.9535/45134/4440.9682/99271/8760.91
13368G/AND5rs3899498526/58424/440.77440/47439/380.36966/105863/820.38
13708A/GND571/49759/4090.9669/41856/4220.26140/915115/8310.46
14798T/CCytb484/100399/690.30406/78400/800.82890/178799/1490.56
16126C/TD-loop119/42791/3750.38101/38585/3930.24220/812176/7680.14
16189T/CD-loop476/86395/730.90419/63419/560.55895/149814/1290.70
16391G/AD-loop572/16458/110.70473/13467/100.56104/529925/210.49
16519C/TD-loop367/204303/1590.66307/180296/1800.78674/384599/3390.94
  • * P values were estimated prior to statistical adjustment for covariates (age, gender, and smoking history).