Table 2.

Multivariable-adjusted Odds Ratios and 95% Confidence Intervals for breast cancer risk associated with urinary levels of 15-F2t-IsoP stratified by age, average physical activity level, fruit and vegetable intake, average lifetime alcohol intake, cigarette smoking status, BMI, and menopausal status

Multivariable-adjusted* ORs (95% CIs), by quartile of 15-F2t-IsoP (nmol/mmol creatinine)
<0.450.45-0.640.64-0.99≥0.99
Age (y)
    <501.001.17 (0.60-2.26)0.98 (0.47-2.0)1.57 (0.77-2.05)
    >501.001.38 (0.76-2.50)2.06 (1.19-3.56)2.35 (1.36-4.07)
Average physical activity level (h/wk)
    <0.71.001.25 (0.67-2.30)1.48 (0.82-2.68)1.55 (0.84-2.85)
    >0.71.001.11 (0.59-2.11)1.51 (0.80-2.84)2.19 (1.20-3.99)
Fruit and vegetable intake (no. 1/2 cup serving/wk)
    <271.001.07 (0.56-2.06)0.88 (0.46-1.68)1.87 (0.98-3.55)
    >271.001.40 (0.76-2.58)2.52 (1.37-4.63)2.04 (1.13-3.69)
Average lifetime alcohol intake (g/d)
    Nondrinkers1.000.92 (0.45-1.87)1.61 (0.80-3.22)1.48 (0.76-2.86)
    <151.001.49 (0.79-2.80)1.35 (0.72-2.52)2.13 (1.11-4.06)
    >151.001.72 (0.44-6.77)1.99 (0.52-7.61)2.06 (0.54-7.90)
Active cigarette smoking status
    Never1.001.49 (0.81-2.75)1.59 (0.85-2.97)2.29 (1.22-4.29)
    Current1.001.08 (0.27-4.29)1.82 (0.53-6.28)2.66 (0.78-9.11)
    Former1.001.08 (0.51-2.30)1.48 (0.70-3.14)1.27 (0.60-2.70)
BMI (kg/m2)
    <251.000.99 (0.51-1.93)1.99 (1.02-3.89)2.04 (1.11-3.74)
    ≥251.001.30 (0.71-2.38)1.30 (0.73-2.31)1.79 (0.97-3.29)
Menopausal status
    Premenopausal1.001.13 (0.57-2.20)1.16 (0.56-2.41)1.85 (0.91-3.76)
    Postmenopausal1.001.40 (0.75-2.60)1.93 (1.08-3.45)2.06 (1.15-3.69)
  • * Adjusted for all other factors in the table.