Table 3.

Polyamine levels at baseline and 3 months in forearm biopsies from subjects with sun damage, AK, or a previous SCC

GroupSamplenAverage (SE)P*
Group 1: sun-damaged forearm, no sunscreenPutrescine baseline2062.65 (4.32)0.3221
Putrescine 3 mo2068.10 (2.97)
Spermine baseline20157.36 (5.72)0.2100
Spermine 3 mo20168.46 (6.40)
Spermidine baseline20178.00 (6.36)0.3776
Spermidine 3 mo20188.02 (7.83)
Total baseline20398.00 (14.44)0.3051
Total 3 mo20440.06 (30.41)
Group 1: sun-damaged forearm, sunscreenPutrescine baseline2265.31 (4.34)0.8785
Putrescine 3 mo2266.07 (3.06)
Spermine baseline22172.67 (8.07)0.6717
Spermine 3 mo22176.91 (4.49)
Spermidine baseline22186.26 (8.75)0.2904
Spermidine 3 mo22197.53 (4.67)
Total baseline22424.25 (18.96)0.5645
Total 3 mo22444.91 (21.30)
Group 2: AK forearmPutrescine baseline2282.21 (4.92)0.7771
Putrescine 3 mo2281.17 (3.71)
Spermine baseline22182.27 (6.95)0.5674
Spermine 3 mo22185.16 (7.81)
Spermidine baseline22209.59 (8.70)0.9558
Spermidine 3 mo22209.26 (8.78)
Total baseline22474.07 (19.41)0.9939
Total 3 mo22474.23 (23.32)
Group 3: previous SCC forearmPutrescine baseline2881.66 (4.27)0.9017
Putrescine 3 mo2882.30 (4.43)
Spermine baseline28177.71 (5.81)0.9060
Spermine 3 mo28178.65 (7.06)
Spermidine baseline28204.57 (5.66)0.9593
Spermidine 3 mo28204.96 (7.30)
Total baseline28463.94 (13.40)0.9218
Total 3 mo28466.95 (26.58)
  • * Paired t tests.