Table 3.

Association (estimated OR and 95% CL) between cumulative marijuana use and cancer incidence among subjects who never used cigarettes, by type of cancer, amount of marijuana use, and covariate adjustment

Cancer type (marijuana use)Cases, NControls, NCrude OR (95% CL)Adjusted OR (95% CL)
Model 1Model 2
Oral cancer
    Never57294111
    >0 to <1 joint-years251380.93 (0.56, 1.6)0.86 (0.51, 1.5)0.93 (0.53, 1.6)
    1 to <10 joint-years11341.7 (0.80, 3.5)1.5 (0.68, 3.1)1.5 (0.68, 3.5)
    ≥10 joint-years9212.2 (0.96, 5.1)2.0 (0.82, 4.7)1.8 (0.69, 4.7)
Pharyngeal cancer
    Never30294111
    Ever131930.66 (0.34, 1.3)0.61 (0.30, 1.2)0.92 (0.41, 2.1)
Laryngeal cancer
    Never7296111
    Ever61931.3 (0.44, 4.0)0.97 (0.31, 3.0)1.2 (0.26, 5.5)
Esophageal cancer
    Never14293111
    Ever91920.98 (0.42, 2.3)0.92 (0.37, 2.2)0.79 (0.30, 2.1)
Lung cancer
    Never91291111
    >0 to <1 joint-years101360.24 (0.12, 0.47)0.26 (0.13, 0.53)0.44 (0.21, 0.92)
    ≥1 joint-years9550.52 (0.25, 1.1)0.63 (0.29, 1.4)1.1 (0.48, 2.6)
  • NOTE: Crude estimates are unadjusted for covariates. Model 1 was adjusted for age (four categories: ≤45, 46-50, 51-55, and 56-62) and gender. Model 2 was adjusted for age (four categories), gender, race/ethnicity (four categories), education (five categories), and drink-years.