Table 3.

Continuous univariate and optimal cutpoint analysis

MarkerContinuous univariate PRelative risk
LPHA0.0161.7
Matriptase0.0351.3
EGFR0.3401.5
Lamp-10.0621.2
β1-Integrin0.2701.3
N-Cadherin0.0881.2
  • NOTE: Univariate P values are based on the Cox model using each marker independently as a continuous marker. Relative risks were calculated at the optimal AQUA score (LPHA, >45.7; matriptase, >52.4; EGFR, >49.5; lamp-1, >99.6; β1-integrin, >65.4; and N-cadherin, >27.6). Statistically significant values are in boldface.