Table 4.

Hormone levels [Geometric Mean (95% Confidence Interval)] at baseline and 12 months in exercise intervention participants by change in fitness (VO2 max)

Exercisers
Baseline12 MonthsP*
Androstenedione (pg/mL)
    Decrease or stable VO2 max500 (413-604)418 (370-472)
    1-10% increase in VO2 max578 (494-676)542 (459-640)0.37
    >10% increase in VO2 max§520 (464-582)477 (428-531)0.39
DHEA (ng/mL)
    Decrease or stable VO2 max1.54 (1.07-2.23)1.27 (0.88-1.83)
    1-10% increase in VO2 max2.54 (1.97-3.26)2.29 (1.68-3.12)0.45
    >10% increase in VO2 max2.26 (1.90-2.69)2.08 (1.75-2.47)0.22
DHEA-S (μg/dL)
    Decrease or stable VO2 max41.3 (26.6-64.1)33.7 (22.1-51.2)
    1-10% increase in VO2 max61.1 (43.5-85.9)60.3 (45.7-79.6)0.13
    >10% increase in VO2 max56.5 (45.4-70.3)49.2 (39.9-60.6)0.39
Testosterone (pg/mL)
    Decrease or stable VO2 max177 (151-207)167 (143-194)
    1-10% increase in VO2 max244 (213-280)252 (211-302)0.18
    >10% increase in VO2 max205 (181-232)197 (173-223)0.71
Free testosterone (pg/mL)
    Decrease or stable VO2 max3.9 (3.3-4.6)3.6 (3.0-4.2)
    1-10% increase in VO2 max5.1 (4.3-6.0)5.0 (4.0-6.2)0.35
    >10% increase in VO2 max4.5 (4.0-5.0)4.1 (3.6-4.6)0.95
  • * P value for difference in hormone change from baseline between VO2 max groups (referent is decrease or stable VO2 max group).

  • n = 14.

  • n = 20.

  • § n = 41.