Table 3.

Hormone concentrations [Geometric Mean (95% Confidence Interval)] at baseline and at 3 and 12 months in exercise intervention and control participants by change in percentage body fat

Exercisers
Controls
Baseline3 Months12 MonthsBaseline3 Months12 Months
Androstenedione (pg/mL)
    Gained percentage body fat498 (432-573)505 (433-590)473 (410-546)601 (513-704)562 (479-659)538 (461-628)
    No change in percentage body fat526 (459-603)443 (345-570)551 (437-694)574 (473-696)527 (455-611)502 (434-582)
    Lost 0.5-2% body fat526 (460-602)489 (405-591)470 (424-521)595 (527-672)608 (530-697)526 (467-592)
    Lost >2% body fat558 (472-661)463 (398-540)463 (398-539)557 (471-659)554 (462-664)506 (441-580)
DHEA (ng/mL)
    Gained percentage body fat1.59 (1.12-2.26)1.63 (1.13-2.34)1.46 (1.00-2.14)2.53 (2.08-3.09)2.50 (2.04-3.07)2.26 (1.89-2.72)
    No change in percentage body fat2.16 (1.75-2.67)1.84 (1.28-2.66)2.31 (1.63-3.29)2.54 (2.07-3.11)2.29 (1.89-2.77)2.27 (1.90-2.73)
    Lost 0.5-2% body fat2.26 (1.80-2.84)2.15 (1.62-2.85)1.99 (1.60-2.49)2.55 (2.14-3.04)2.50 (2.18-2.88)2.33 (1.97-2.75)
    Lost >2% body fat2.51 (2.02-3.12)2.18 (1.77-2.67)2.01 (1.63-2.50)1.83 (1.44-2.33)1.81 (1.27-2.57)1.68 (1.32-2.15)
DHEA-S (μg/dL)
    Gained percentage body fat41.9 (29.5-59.5)42.7 (31.8-57.4)37.3 (25.9-53.7)69.4 (53.2-90.4)63.5 (48.3-83.6)63.0 (48.7-81.6)
    No change in percentage body fat52.1 (37.6-72.2)47.3 (29.9-74.8)52.4 (35.0-78.7)63.3 (48.1-83.1)54.5 (40.4-73.6)58.0 (43.6-77.2)
    Lost 0.5-2% body fat52.3 (39.3-69.6)48.1 (35.2-65.7)50.2 (40.2-62.6)64.3 (52.1-79.2)63.2 (50.2-77.0)58.1 (46.3-72.8)
    Lost >2% body fat62.5 (46.3-84.3)55.4 (42.4-72.3)48.9 (36.3-66.0)42.9 (26.6-69.3)43.4 (26.4-71.4)44.3 (28.8-68.2)
Testosterone (pg/mL)
    Gained percentage body fat215 (184-260)233 (191-284)237 (187-300)236 (198-281)217 (182-257)223 (184-269)
    No change in percentage body fat224 (179-281)227 (189-273)234 (194-281)210 (170-260)214 (173-265)213 (168-271)
    Lost 0.5-2% body fat213 (187-243)210 (187-236; P = 0.024)*200 (175-229; P = 0.027)215 (190-242)215 (195-237)209 (190-230)
    Lost >2% body fat199 (173-230)179 (154-207; P = 0.005)*183 (156-213; P = 0.023)248 (196-315)244 (193-308)239 (192-298)
Free testosterone (pg/mL)
    Gained percentage body fat4.8 (4.1-5.7)5.1 (4.2-6.2)5.2 (4.2-6.5)4.8 (3.9-5.8)4.5 (3.7-5.4)4.5 (3.7-5.5)
    No change in percentage body fat4.6 (3.6-6.0)4.4 (3.5-5.6; P = 0.065)*4.8 (3.9-5.9)4.6 (3.8-5.7)4.7 (3.7-5.8)4.7 (3.7-5.9)
    Lost 0.5-2% body fat4.8 (4.2-5.5)4.6 (4.0-5.2; P = 0.033)*4.3 (3.7-4.9; P = 0.010)4.6 (4.1-5.1)4.6 (4.2-5.0)4.4 (4.0-5.0)
    Lost >2% body fat4.1 (3.6-4.7)3.6 (3.1-4.1; P = 0.010)*3.6 (3.1-4.2; P = 0.031)5.4 (4.5-6.6)5.3 (4.3-6.5)5.0 (4.1-6.0)
  • NOTE: The numbers of exercisers who gained, no change, lost 0.5% to 2.0% body fat, and lost >2% body fat were 16, 12, 29, and 26, respectively; the numbers of controls who gained, no change, lost 0.5% to 2.0% body fat, and lost >2% body fat were 27, 20, 25, and 11, respectively.

  • * P value for hormone change from baseline to 3 months in exercisers versus controls within level of percentage body fat change compared with those that gained percentage body fat. P values not presented were >0.05.

  • P value for hormone change from baseline to 12 months in exercisers versus controls within level of percentage body fat change compared with those that gained percentage body fat. P values not presented were >0.05.