Table 4

Prevalence of at least one HFE C282Y allelea in a nontransplant cohort with primary invasive breast cancer compared with United States population-based estimates

Women with invasive breast cancerUnited States population by race/ethnicity and sex
NHWb women (n = 141) % (95% CI)cNHB women (n = 59) % (95% CI)All NHW (n = 2016) % (95% CI)All NHB (n = 1600) % (95% CI)All women (n = 2884) % (95% CI)
18.4 (12.0–24.9)8.5 (1.4–15.6)12.4 (11.0–13.8)2.5 (1.7–3.3)7.2 (6.3–8.1)
  • a Includes C282Y homozygotes and heterozygotes (heterozygotes include C282Y/Wt + C282Y/H63D genotypes); data from Steinberg et al. 22 .

  • b NHW, Non-Hispanic white(s); NHB, Non-Hispanic black(s).

  • c Values are percentage of patients with 95% confidence intervals (95% CIs). There were no C282Y homozygotes among breast cancer cases in the nontransplant cohort.