Table 1

Distribution of markersa of insulin and glucose control in colorectal cases and matched controls nested in the CLUE II cohort of Washington County, Maryland, 1989

MarkerColorectal cancer cases (n = 173)Controls (n = 346)Pb
Insulin,c milliunits/liter (mean ± SD)20.8 ± 23.323.3 ± 30.00.24
HDL-cholesterol, mg/dl (mean ± SD)45.6 ± 13.644.6 ± 13.70.44
Total cholesterol, mg/dl (mean ± SD)216.0 ± 41.4218.4 ± 38.90.45
Ratio of total cholesterol:HDL-cholesterol (mean ± SD)5.1 ± 1.85.5 ± 4.10.10
Triglycerides,c mg/dl (mean ± SD)168.7 ± 98.8173.5 ± 90.80.60
IGFBP-1,c ng/ml (mean ± SD)26.3 ± 32.226.9 ± 32.40.84
HbA1c, % (mean ± SD)5.9 ± 1.15.8 ± 0.90.05
BMI, kg/m2 (%)
 <2539.944.2
 25–29.938.241.30.10
 ≥3022.014.5
Use of medications to treat diabetes (%)8.13.50.04
  • a Measurements were unavailable for some participants because of insufficient plasma volume. Included in the analysis were sets for which the case and at least one control had information available. The counts are insulin 172 cases, 344 controls; HDL-cholesterol 170 cases, 331 controls; total cholesterol 173 cases, 344 controls; ratio of cholesterol:HDL-cholesterol 170 cases and 329 controls; triglycerides 170 cases, 334 controls; and IGFBP-1169 cases, 335 controls.

  • b P reported for the test of no difference in means (ANOVA) or proportions (McNemar’s test) between cases and controls matched on age, sex, race, time since last meal, and date of blood draw.

  • c 79.8% of participants reported last meal <6 h before blood draw (i.e., nonfasting samples).