Table 6

Pharmacokinetic parameters for free plasma genistein

Genistein dose level (mg/kg)43% Genistein preparation90% Genistein preparation
No. of patientsTmaxab (h)Cmaxc (nm)No. of patientsTmaxb (h)Cmax (nm)
243.25 (2–24)66.4 (46.3)43.0 (0.5–10)116.9 (116.6)
433.0 (2–4.5)169.8 (27.5)26.0 (2–10)108.7 (116.2)
833.0 (2–3)154.8 (96.6)23.25 (2–4.5)53.2 (42.7)
  • a Tmax, time of maximal plasma concentration; Cmax, maximal plasma concentration.

  • b Median and range.

  • c Means and SDs.