Univariate analysis of risk factors of appendicular bone sarcoma in a cohort of 683 Rottweiler dogs
| Risk Factor | Dogs with bone sarcoma | Dogs without bone sarcoma | Hazard Ratio (95% CI) | P |
|---|---|---|---|---|
| Total no. | 86 dogs | 597 dogs | ||
| Gender | ||||
| Male | 35 dogs | 259 dogs | 1.00 | |
| Female | 51 dogs | 338 dogs | 1.01 (0.66–1.55) | 0.97 |
| Neuter status | ||||
| Intact male | 10 dogs | 120 dogs | 1.00 | |
| Castrated male | 25 dogs | 139 dogs | 1.86 (0.89–3.87) | 0.10 |
| Intact female | 5 dogs | 64 dogs | 1.00 | |
| Spayed female | 46 dogs | 274 dogs | 0.95 (0.38–2.40) | 0.91 |
| Lifetime gonadal exposure | ||||
| Months intact (mean± SD) | ||||
| Male | 53.1 ± 44.3 mo | 71.1 ± 42.7 mo | 0.98 (0.98–0.99) | <0.0001 |
| Female | 40.5 ± 34.0 mo | 55.6 ± 35.0 mo | 0.98 (0.97–0.99) | <0.0001 |
| Body size | ||||
| Adult height (mean± SD) | ||||
| Male | 61.0 ± 2.8 cm | 65.8 ± 2.8 cm | 1.10 (0.97–1.26) | 0.15 |
| Female | 24.0 ± 1.1 cm | 61.0 ± 3.3 cm | 1.00 (0.91–1.10) | 0.97 |
| Adult body weight (mean± SD) | ||||
| Male | 50.5 ± 7.6 kg | 49.7 ± 5.7 kg | 1.04 (0.99–1.10) | 0.15 |
| Female | 40.9 ± 4.7 kg | 40.6 ± 5.0 kg | 1.01 (0.96–1.01) | 0.74 |