Table 2

Univariate analysis of risk factors of appendicular bone sarcoma in a cohort of 683 Rottweiler dogs

Risk FactorDogs with bone sarcomaDogs without bone sarcomaHazard Ratio (95% CI)P
Total no.86 dogs597 dogs
Gender
 Male35 dogs259 dogs1.00
 Female51 dogs338 dogs1.01 (0.66–1.55)0.97
Neuter status
 Intact male10 dogs120 dogs1.00
 Castrated male25 dogs139 dogs1.86 (0.89–3.87)0.10
 Intact female 5 dogs 64 dogs1.00
 Spayed female46 dogs274 dogs0.95 (0.38–2.40)0.91
Lifetime gonadal exposure
 Months intact (mean± SD)
  Male53.1 ± 44.3 mo71.1 ± 42.7 mo0.98 (0.98–0.99)<0.0001
  Female40.5 ± 34.0 mo55.6 ± 35.0 mo0.98 (0.97–0.99)<0.0001
Body size
 Adult height (mean± SD)
  Male61.0 ± 2.8 cm65.8 ± 2.8 cm1.10 (0.97–1.26)0.15
  Female24.0 ± 1.1 cm61.0 ± 3.3 cm1.00 (0.91–1.10)0.97
 Adult body weight (mean± SD)
  Male50.5 ± 7.6 kg49.7 ± 5.7 kg1.04 (0.99–1.10)0.15
  Female40.9 ± 4.7 kg40.6 ± 5.0 kg1.01 (0.96–1.01)0.74