Table 4

Age-adjusted odds of CMM by GST genotype stratified by pigmentation characteristic

Hair colorEye colorSkin reaction to acute sunSkin reaction to chronic sunFreckling
Brown or blackRed, reddish-brown, or blondLight or dark brownBlue, gray, green, or hazelBurn then tan or tanBurn without tanningMedium or dark tanLight or no tanNoneAny
Case/controlORa95% CICase/controlORa95% CICase/controlORa95% CICase/controlORa95% CICase/controlORa95% CICase/controlORa95% CICase/controlORa95% CICase/controlORa95% CICase/controlORa95% CICase/controlORa95% CI
GSTM1 active 126/1051.057/421.041/491.0138/961.087/691.096/771.0103/1031.075/401.034/521.0149/951.0
GSTM1 null 117/1030.99(0.68–1.4)62/212.2(1.2–4.2)55/551.3(0.72–2.2)124/691.3(0.85–1.9)90/740.99(0.63–1.6)89/491.5(0.94–2.4)106/951.1(0.76–1.7)72/281.4(0.79–2.6)32/461.1(0.57–2.1)147/781.2(0.84–1.8)
GSTT1 active 194/1541.092/511.075/821.0207/1211.0143/1121.0143/911.0162/1511.0118/501.052/761.0234/1291.0
GSTT1 null 49/540.71(0.45–1.1)27/121.3(0.58–2.7)21/221.1(0.54–2.1)55/440.71(0.45–1.1)34/310.83(0.48–1.5)42/350.77(0.45–1.3)47/470.94(0.59–1.5)29/180.66(0.33–1.3)14/220.84(0.38–1.9)62/440.79(0.50–1.2)
GST active 211/1791.0103/621.081/931.0229/1461.0152/1281.0162/1111.0179/1761.0129/601.057/901.0257/1511.0
GST null 32/290.97(0.56–1.7)16/19.5(1.2–73)15/111.7(0.72–3.9)33/191.1(0.60–2.0)25/151.4(0.69–2.8)23/151.1(0.54–2.2)30/221.4(0.77–2.6)18/80.99(0.40–2.5)9/81.8(0.61–5.1)39/221.1(0.61–1.9)
  • a Adjusted for age.