Table 3

Soy food and other dietary intake during adolescence and risk of breast cancer, The Shanghai Breast Cancer Study, 1996–1998

Adjusted ORs (95% CI) by quintilea,b,cTrend test P
Q1 (low)Q2Q3Q4Q5
 A. Premenopausal women (952 cases and 990 controls)
Soy foods (total)1.000.75 (0.57–1.00)0.72 (0.54–0.96)0.64 (0.48–0.85)0.53 (0.39–0.72)<0.01
 Bean curd (tofu)1.000.73 (0.56–0.92)0.87 (0.64–1.20)0.60 (0.45–0.79)0.79 (0.58–1.08)0.02
 Soy milk1.000.67 (0.55–0.82)
 Soy products other than tofu1.000.90 (0.65–1.23)0.76 (0.52–1.10)0.68 (0.48–0.96)0.01
Fresh legumesd1.001.04 (0.76–1.41)1.04 (0.82–1.33)0.86 (0.64–1.15)0.96 (0.72–1.29)0.51
Dried beanse1.000.91 (0.72–1.15)0.85 (0.66–1.10)0.77 (0.57–1.05)0.07
 B. Postmenopausal women (501 cases and 562 controls)
Soy foods (total)1.000.69 (0.48–1.01)0.65 (0.44–0.97)0.79 (0.54–1.16)0.49 (0.33–0.74)<0.01
 Bean curd (tofu)1.001.10 (0.77–1.57)0.89 (0.58–1.38)0.82 (0.56–1.19)0.62 (0.41–0.93)0.01
 Soy milk1.000.98 (0.73–1.32)0.89
 Soy products other than tofu1.000.77 (0.53–1.12)0.93 (0.57–1.53)0.62 (0.41–0.94)0.05
Fresh legumesd1.000.77 (0.50–1.19)0.92 (0.65–1.30)0.83 (0.55–1.27)0.96 (0.67–1.39)0.82
Dried beanse1.000.70 (0.50–0.97)0.67 (0.46–0.95)0.76 (0.53–1.08)0.03
 C. Data reported by mothers among women <40 years of age (296 cases and 359 controls)
Soy foods (total)1.000.70 (0.45–1.09)0.59 (0.32–1.07)0.60 (0.37–0.99)0.35 (0.21–0.60)<0.01
 Bean curd (tofu)1.001.08 (0.70–1.65)0.72 (0.41–1.27)0.52 (0.31–0.85)0.65 (0.37–1.17)<0.01
 Soy milk1.000.89 (0.61–1.31)0.56
 Soy products other than tofu1.001.10 (0.67–1.79)0.72 (0.45–1.17)0.79 (0.46–1.33)0.44 (0.25–0.79)<0.01
Fresh legumesd1.000.52 (0.30–0.92)0.88 (0.57–1.38)1.05 (0.63–1.75)0.67 (0.40–1.12)0.55
Dried beanse1.000.94 (0.62–1.44)0.73 (0.46–1.16)0.63 (0.40–1.01)0.04
  • a ORs were compared to the lowest quintile of intake and adjusted for intake level of rice and wheat products, age, education, family history of breast cancer, history of breast fibroadenoma, WHR, age at menarche, physical activity, ever had live birth, menopausal status, and age at menopause.

  • b Ever versus never for analyses of foods rarely consumed.

  • c Tertile distribution of intake for analyses of foods when a large number of subjects did not eat the foods.

  • d Commonly consumed fresh legumes include peas, string beans, kidney beans, and, less commonly consumed fresh legumes include soy beans.

  • e Commonly consumed dry beans are soy bean seeds, mung beans, and red beans.