Table 4

Linear regression analysis of MDA and antral, plasma, and gastric juice ascorbic acid and total vitamin C, with M1-dG as the dependent variable, before and after adjustment for H. pylori infection

Univariate analysisAdjusted for H. pylori infection
Regression slopea (95% CI)PRegression slopea (95% CI)P
Log MDA0.28 (−0.04 to 0.59)0.090.44 (0.08 to 0.81)0.02
Log antral AAb0.19 (0.05 to 0.34)0.0090.19 (0.05 to 0.34)0.009
Log antral TVC0.24 (0.06 to 0.42)0.0090.24 (0.06 to 0.42)0.008
Log gastric Juice AA0.11 (0.002 to 0.21)0.05−0.10 (−0.02 to 0.21)0.09
Log gastric Juice TVC0.11 (−0.03 to 0.24)0.1−0.10 (−0.06 to 0.25)0.2
Log plasma AA−0.05 (−0.19 to 0.08)0.5−0.06 (−0.20 to 0.08)0.4
Log plasma TVC−0.04 (−0.22 to 0.13)0.6−0.06 (−0.25 to 0.12)0.5
  • a The regression slope represents the increase in log M1-dG for each unit increase in the log-transformed variable.

  • b AA, ascorbic acid; TVC, total vitamin C.