Table 4

Comparison of molecular factors in tissue from biopsies taken from fatty and dense sites (unpaired)

Fatty tissue at biopsy siteDense tissue at biopsy sitePa
Percentage of nuclear area1.01 (0.54–2.33)b2.52 (1.06–5.00)0.0004
0.17 c 0.87
n = 40n = 51
Percentage of total collagen11.69 (3.49–33.48)35.54 (10.98–62.70)0.002
2.14 3.02
n = 35n = 48
Percentage of IGF-11.13 (0.21–2.64)1.94 (0.75–4.06)0.05
−0.32 0.44
n = 40n = 50
Percentage of TGF-α0.30 (0.06–0.81)0.42 (0.11–1.32)0.30
−1.70 −1.21
n = 39n = 51
Percentage of TIMP-30.45 (0.05–3.63)0.54 (0.06–5.93)0.45
−0.81 −0.39
n = 40n = 51
  • a P for two sample Wilcoxon tests comparing median values.

  • b Median (interquartile range) of untransformed values.

  • c Mean of log-transformed data in italics to allow comparison with Tables 2<$REFLINK> and 3<$REFLINK> .