Table 4.

Multivariate associations between selected male smoking characteristics and risk of CIN-3/CIS or ICC

OR (95% CI)
Male smoking characteristicsAll couplesCouples with monogamous women
CIN-3/CISa
Time since smoking cessation
 Nonsmoker1.001.00
 Ever smoker1.33 (0.89–1.99)1.16 (0.71–1.88)
 Ex-smoker >11 years1.51 (0.53–4.31)0.84 (0.22–3.19)
 Ex-smoker ≤10 years1.17 (0.58–2.34)0.67 (0.24–1.87)
 Current smoker1.36 (0.88–2.07)1.26 (0.76–2.09)
Use of tobacco type by smokers
 Blond1.001.00
 Black0.49 (0.23–1.06)0.33 (0.12–0.88)
 Both0.49 (0.24–0.99)0.36 (0.14–0.91)
 Others0.89 (0.12–6.39)1.03 (0.07–15.53)
Use of smoking filter type by smokers
 Filter1.001.00
 No filter0.76 (0.29–1.96)0.49 (0.14–1.68)
 Both0.78 (0.45–1.32)0.61 (0.31–1.18)
 Others1.63 (0.25–10.73)2.79 (0.21–36.93)
Smoking lifetime pack-yearsc
 Nonsmoker1.001.00
 Low no. of pack-years1.18 (0.75–1.85)0.89 (0.51–1.57)
 Medium/high no. of pack-years1.52 (0.93–2.47)1.45 (0.53–2.56)
ICCb
Time since smoking cessation
 Nonsmoker1.001.00
 Ever smoker1.57 (1.15–2.15)1.55 (1.07–2.23)
 Ex-smoker >11 years1.46 (0.84–2.52)1.11 (0.60–2.07)
 Ex-smoker ≤10 years1.50 (0.95–2.37)1.59 (0.95–2.67)
 Current smoker1.61 (1.16–2.24)1.63 (1.11–2.40)
P trend0.0060.01
Use of tobacco type by smokers
 Blond1.001.00
 Black0.91 (0.27–3.04)0.63 (0.17–2.33)
 Both1.42 (0.40–5.10)0.83 (0.21–3.31)
 Others0.85 (0.32–2.27)0.66 (0.21–2.08)
Use of smoking filter type by smokers
 Filter1.001.00
 No filter1.34 (0.55–3.27)0.95 (0.33–2.69)
 Both1.41 (0.72–2.72)1.31 (0.63–2.71)
 Others0.98 (0.38–2.55)0.83 (0.27–2.54)
Smoking lifetime pack-yearsd
 Nonsmoker1.001.00
 Low no. of pack-years1.62 (1.14–2.29)1.64 (1.09–2.47)
 Medium/high no. of pack-years1.48 (1.03–2.12)1.39 (0.91–2.10)
  • aCIS multivariate model was adjusted for age of the husband and wife, study country, interaction terms (lifetime number of sexual partners of husband × study country and circumcision status × study country), age at first sexual intercourse of the wife (≥21 years, 17–20 years, ≤16 years), lifetime number of sexual partners of wife (1, ≥2); and husbands with monogamous women model was adjusted for all variables in the table except for circumcision, interaction term (lifetime number of sexual partners of husband × study country), age of the wife and age at first sexual intercourse of the wife.

  • bICC model for all husbands and husbands with monogamous women were adjusted for age of the husband and wife, study country, interaction term (lifetime number of sexual partners of husband × study country), level of education of the husband and wife (≥secondary level, primary level, no schooling), history of STIs, age at first sexual intercourse of the wife (≥21 years, 17–20 years, ≤16 years), lifetime smoking pack-years of the wife (nonsmoker, low, medium, and high smoking lifetime-pack-years), oral contraceptive use (never, 1–4 years, ≥5 years), parity (nulliparous, 1–6, ≥7), pap smear history 12 months prior to study enrollment (never, ever), and lifetime number of sexual partners of the wife (1, ≥2).

  • cCIN-3/CIS model: Smoking lifetime pack-years for all husbands model is defined as low (36.5–6,022.5 pack-years) and medium/high (6,132–56,611.5 pack-years); and for the husbands with monogamous women model, low (36.5–6,716 pack-years) and medium/high (6,825.5–38,963.8 pack-years).

  • dICC model: Smoking lifetime pack-years for the all husbands model is defined as: low (36.5–7,300 pack-years) and medium/high (7,354.8–43,435 pack-years); and for the husbands with monogamous women model, low (36.5–7,665 pack-years) and medium/high (7,829.3–43,435 pack-years).