Table 3.

Invasive colorectal cancer outcomes (annualized%) for White and African American women

Model 1aModel 2b
N (Annualized%)HR (95% CI)HR (95% CI)
Proximal invasive colorectal cancer
  White882(0.06%)1.001.00
  African–American103(0.07%)1.25(1.02, 1.54)1.18(0.91, 1.51)
P-valuec0.030.21
Distal invasive colorectal cancer
  White403(0.03%)1.001.00
  African–American46(0.03%)1.07(0.79, 1.46)0.96(0.64, 1.42)
P-valuec0.660.83
Invasive rectal cancerd
  White318(0.02%)1.001.00
  African–American34(0.02%)0.99(0.69, 1.41)0.70(0.43, 1.12)
P-valuec0.950.13
Death from colorectal cancer
  White411(0.03%)1.001.00
  African–American51(0.04%)0.92(0.69, 1.24)0.78(0.53, 1.13)
P-valuec0.590.18
  • aAdjusted for age and stratified on WHI trial and extension study participation.

  • bAdjusted for age, education, diabetes, body mass index, physical activity, smoking, alcohol use, NSAID use, total dietary energy, dietary fiber, red meat, fruits and vegetables, total calcium intake, prior colon screening, history of colon polyp removal, family history of colorectal cancer, and prior menopausal hormone use and stratified on WHI trial and extension study participation.

  • cP-value is from a Wald χ2 test for the main effect of race/ethnicity.

  • dIncludes rectum and rectosigmoid junction sites.