Decades of investment into genomic science has led to a revolution in our understanding of the architecture of the human genome, genomic variation, and the biological consequences of the genome on human health and disease. Thanks to the technical and methodological advancements that enabled Genome-Wide Association Studies (GWAS), our understanding of the underlying genetics of most common diseases and traits has been fundamentally changed. In this special CEBP Focus issue, some of the leading figures in GWAS research in the past decades summarize what we have learned from this line of research and where the field can contribute biological and clinical insights into cancer.
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Editorial: The Fruits of the Genomic Revolution
Sellers TA and Rebbeck TR Cancer Epidemiology, Biomarkers & Prevention April 2018. -
A decade of GWAS results in lung cancer
Bossé Y and Amos CI Cancer Epidemiology, Biomarkers & Prevention April 2018. -
Common Genetic Variation and Breast Cancer Risk - Past, present, and futur
Lilyquist J Couch FJ Cancer Epidemiology, Biomarkers & Prevention April 2018. -
Common Genetic Variation and Susceptibility to Ovarian Cancer: Current Insights and Future Directions
Kar SP Pharoah PDP Cancer Epidemiology, Biomarkers & Prevention April 2018. -
Genome-wide association studies of cancer in diverse populations
Park SL Haiman CA Cancer Epidemiology, Biomarkers & Prevention April 2018. -
Genome-wide association studies in glioma
Kinnersley B Bondy ML Cancer Epidemiology, Biomarkers & Prevention April 2018.
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