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Cancer Epidemiology, Biomarkers & Prevention
Cancer Epidemiology, Biomarkers & Prevention

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Research Article

Aspirin Use Reduces the Risk of Aggressive Prostate Cancer and Disease Recurrence in African-American Men

Cheryl Jacobs Smith, Tiffany H. Dorsey, Wei Tang, Symone V. Jordan, Christopher A. Loffredo and Stefan Ambs
Cheryl Jacobs Smith
Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, Maryland.
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Tiffany H. Dorsey
Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, Maryland.
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Wei Tang
Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, Maryland.
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Symone V. Jordan
Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, Maryland.
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Christopher A. Loffredo
Cancer Prevention and Control Program, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC.
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Stefan Ambs
Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, Maryland.
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  • For correspondence: ambss@mail.nih.gov
DOI: 10.1158/1055-9965.EPI-16-1027
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    • Supplementary Tables 1-7 - Tables S1-S7. Table S1. Characteristics of all cases and population controls in the NCI Maryland Prostate Cancer Case-Control Study. Table S2. Pain reliever use of participants in the NCI Maryland Prostate Cancer Case-Control Study. Table S3. Adjusteda odds ratios and 95% confidence intervals for associations of regular aspirin use and prostate cancer risk in the NCI Maryland Prostate Cancer Case-Control Study. Table S4. Adjusteda odds ratios and 95% confidence intervals for associations of regular aspirin use and prostate cancer risk in men with low stageb disease compared to population controls. Table S5. Adjusteda odds ratios and 95% confidence intervals for associations of regular aspirin use and prostate cancer risk in men with high stageb disease compared to controls. Table S6. Adjusteda odds ratios and 95% Confidence intervals for associations of regular aspirin use and prostate cancer risk in men with aggressiveb disease compared to population controls. Table S7. Adjusteda odds ratios and 95% confidence intervals for associations of regular aspirin use and prostate cancer risk in men with nonaggressiveb disease compared to populations controls.
    • Supplementary Figures - Supplementary Figure 1. Increased C-reactive protein (CRP) plasma level in African-American (AA) men. Differences in CRP plasma level between AA and European-American(EA) men. CRP was measured in plasma samples of cases (100 AA, 100 EA) and controls(100 AA, 100 EA).
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Published OnlineFirst May 18, 2017
doi: 10.1158/1055-9965.EPI-16-1027

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Aspirin Use Reduces the Risk of Aggressive Prostate Cancer and Disease Recurrence in African-American Men
Cheryl Jacobs Smith, Tiffany H. Dorsey, Wei Tang, Symone V. Jordan, Christopher A. Loffredo and Stefan Ambs
Cancer Epidemiol Biomarkers Prev May 18 2017 DOI: 10.1158/1055-9965.EPI-16-1027

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Aspirin Use Reduces the Risk of Aggressive Prostate Cancer and Disease Recurrence in African-American Men
Cheryl Jacobs Smith, Tiffany H. Dorsey, Wei Tang, Symone V. Jordan, Christopher A. Loffredo and Stefan Ambs
Cancer Epidemiol Biomarkers Prev May 18 2017 DOI: 10.1158/1055-9965.EPI-16-1027
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Cancer Epidemiology, Biomarkers & Prevention
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