Table of Contents

High Birthweight and Cancer: Evidence and Implications

• Julie A. Ross

Does “Clock” Matter in Prostate Cancer?

• Yong Zhu,
• Tongzhang Zheng,
• Richard G. Stevens,
• Yawei Zhang,
• and Peter Boyle

Genetic Epidemiology: the Value of Population Differences

• Maria Elena Martinez

Uptake of the Tobacco-Specific Lung Carcinogen 4-(Methylnitrosamino)-1-(3-pyridyl)-1-Butanone by Moldovan Children

• Irina Stepanov,
• Stephen S. Hecht,
• Gheorghe Duca,
• and Igor Mardari

A Randomized Controlled Trial of Financial Incentives for Smoking Cessation

• Kevin G. Volpp,
• Andrea Gurmankin Levy,
• David A. Asch,
• Jesse A. Berlin,
• John J. Murphy,
• Angela Gomez,
• Harold Sox,
• Jingsan Zhu,
• and Caryn Lerman

Mitochondrial DNA Content Increase in Response to Cigarette Smoking

• Brett G. Masayesva,
• Elizabeth Mambo,
• Rodney J. Taylor,
• Olga G. Goloubeva,
• Shaoyu Zhou,
• Yoram Cohen,
• Khalid Minhas,
• Wayne Koch,
• James Sciubba,
• Anthony J. Alberg,
• David Sidransky,
• and Joseph Califano

Unlimited Access to Care: Effect on Racial Disparity and Prognostic Factors in Lung Cancer

• Charles R. Mulligan,
• Amir D. Meram,
• Courtney D. Proctor,
• Hongyu Wu,
• Kangmin Zhu,
• and Aizen J. Marrogi

The Relative Use of Eight Collagenous and Noncollagenous Markers for Diagnosis of Skeletal Metastases in Breast, Prostate, or Lung Cancer Patients

• Diana J. Leeming,
• Mitsuru Koizumi,
• Inger Byrjalsen,
• Bo Li,
• Per Qvist,
• and László B. Tankó

Estrogen and Progesterone Levels in Nipple Aspirate Fluid of Healthy Premenopausal Women: Relationship to Steroid Precursors and Response Proteins

• Peter H. Gann,
• Angela S. Geiger,
• Irene B. Helenowski,
• Edward F. Vonesh,
• and Robert T. Chatterton

Reduction in Breast Cancer Mortality from Organized Service Screening with Mammography: 1. Further Confirmation with Extended Data

Reduction in Breast Cancer Mortality from the Organised Service Screening with Mammography: 2. Validation with Alternative Analytic Methods

Effect of Physical Activity on Women at Increased Risk of Breast Cancer: Results from the E3N Cohort Study

• Bertrand Tehard,
• Christine M. Friedenreich,
• Jean-Michel Oppert,
• and Francoise Clavel-Chapelon

Clinical Stage of Breast Cancer by Parity, Age at Birth, and Time Since Birth: A Progressive Effect of Pregnancy Hormones?

• Grethe Albrektsen,
• Ivar Heuch,
• Steinar Thoresen,
• and Gunnar Kvåle

Complementary Medicine Use before and 1 Year Following Genetic Testing for BRCA1/2 Mutations

• Lisa M. DiGianni,
• Montserrat Rue,
• Karen Emmons,
• and Judy E. Garber

The AIB1 Polyglutamine Repeat Does Not Modify Breast Cancer Risk in BRCA1 and BRCA2 Mutation Carriers

• Amanda B. Spurdle,
• Antonis C. Antoniou,
• Livia Kelemen,
• Helene Holland,
• Susan Peock,
• Margaret R. Cook,
• Paula L. Smith,
• Mark H. Greene,
• Jacques Simard,
• Marie Plourde,
• Melissa C. Southey,
• Andrew K. Godwin,
• Jeanne Beck,
• Alexander Miron,
• Mary B. Daly,
• Regina M. Santella,
• John L. Hopper,
• Esther M. John,
• Irene L. Andrulis,
• Francine Durocher,
• Jeffery P. Struewing,
• Douglas F. Easton,
• Georgia Chenevix-Trench,
• Australian Breast Cancer Family Study,
• Australian Jewish Breast Cancer Study,
• Breast Cancer Family Registry,
• Interdisciplinary Health Research International Team on Breast Cancer Susceptibility,
• The Kathleen Cunningham Foundation Consortium for Research into Familial Breast Cancer,
• and Epidemiological Study of Familial Breast Cancer Study Collaborators

p53 Mutation Analysis in Breast Tumors by a DNA Microarray Method

• Meredith Tennis,
• Shiva Krishnan,
• Matthew Bonner,
• Christine B. Ambrosone,
• John E. Vena,
• Kirsten Moysich,
• Helen Swede,
• Susan McCann,
• Per Hall,
• Peter G. Shields,
• and Jo L. Freudenheim

Circulating Steroid Hormones and the Risk of Prostate Cancer

• Gianluca Severi,
• Howard A. Morris,
• Robert J. MacInnis,
• Dallas R. English,
• Wayne Tilley,
• John L. Hopper,
• Peter Boyle,
• and Graham G. Giles

A Prospective Study of Lycopene and Tomato Product Intake and Risk of Prostate Cancer

• Victoria A. Kirsh,
• Susan T. Mayne,
• Ulrike Peters,
• Nilanjan Chatterjee,
• Michael F. Leitzmann,
• L. Beth Dixon,
• Donald A. Urban,
• E. David Crawford,
• and Richard B. Hayes

Effect of NAT1 and NAT2 Genetic Polymorphisms on Colorectal Cancer Risk Associated with Exposure to Tobacco Smoke and Meat Consumption

• Carmen Lilla,
• Emaculate Verla-Tebit,
• Angela Risch,
• Birgit Jäger,
• Michael Hoffmeister,
• Hermann Brenner,
• and Jenny Chang-Claude

Cutting Cost and Increasing Access to Colorectal Cancer Screening: Another Approach to Following the Guidelines

• Judith A. Fisher,
• Christopher Fikry,
• and Andrea B. Troxel

Discovery of Novel Methylation Biomarkers in Cervical Carcinoma by Global Demethylation and Microarray Analysis

• Pavel Sova,
• Qinghua Feng,
• Gary Geiss,
• Troy Wood,
• Robert Strauss,
• Vania Rudolf,
• Andre Lieber,
• and Nancy Kiviat

Evaluating Bias due to Population Stratification in Epidemiologic Studies of Gene-Gene or Gene-Environment Interactions

• Yiting Wang,
• Russell Localio,
• and Timothy R. Rebbeck

How Well Do HapMap Haplotypes Identify Common Haplotypes of Genes? A Comparison with Haplotypes of 334 Genes Resequenced in the Environmental Genome Project

• Jack A. Taylor,
• Zong-Li Xu,
• Norman L. Kaplan,
• and Richard W. Morris

Variation of the N-Acetyltransferase 2 Gene in a Romanian and a Kyrgyz Population

• Sylvia Rabstein,
• Klaus Unfried,
• Ulrich Ranft,
• Thomas Illig,
• Melanie Kolz,
• Hans-Peter Rihs,
• Chinara Mambetova,
• Mariana Vlad,
• Thomas Brüning,
• and Beate Pesch

Sun-Protective Behavior among Individuals with a Family History of Melanoma

• Lora M. Azzarello,
• Sophie Dessureault,
• and Paul B. Jacobsen

Eliminating Carcinogenic Acetaldehyde By Cysteine From Saliva During Smoking

• Ville J. Salaspuro,
• Jaana M. Hietala,
• Martti L. Marvola,
• and Mikko P. Salaspuro

Intentions to Participate in Genetics Research among African American Smokers

• Chanita Hughes Halbert,
• Oscar H. Gandy, Jr.,
• Aliya Collier,
• and Lee Shaker

Smoking Rates and Topography Predict Adolescent Smoking Cessation Following Treatment with Nicotine Replacement Therapy

• Frederick H. Franken,
• Wallace B. Pickworth,
• David H. Epstein,
• and Eric T. Moolchan

Combined Effects of the p53 and p73 Polymorphisms on Lung Cancer Risk

• Matthew B. Schabath,
• Xifeng Wu,
• Qingyi Wei,
• Guojun Li,
• Jian Gu,
• and Margaret R. Spitz

Breast Cancer Risk Reduction Options: Awareness, Discussion, and Use among Women from Four Ethnic Groups

• Celia Patricia Kaplan,
• Jennifer S. Haas,
• Eliseo J. Pérez-Stable,
• Steven E. Gregorich,
• Carol Somkin,
• Genevieve Des Jarlais,
• and Karla Kerlikowske

Dietary Patterns and Risk of Prostate Cancer in U.S. Men

• Kana Wu,
• Frank B. Hu,
• Walter C. Willett,
• and Edward Giovannucci

IGF-I Genetic Variation and Breast Cancer: the Multiethnic Cohort

• Veronica Wendy Setiawan,
• Iona Cheng,
• Daniel O. Stram,
• Kathryn L. Penney,
• Loic Le Marchand,
• David Altshuler,
• Laurence N. Kolonel,
• Joel Hirschhorn,
• Brian E. Henderson,
• and Matthew L. Freedman

No Association Between the MDM2 −309 T/G Promoter Polymorphism and Breast Cancer in African-Americans or Whites

• Robert C. Millikan,
• Kimberley Heard,
• Scott Winkel,
• Edgar J. Hill,
• Kristin Heard,
• Beri Massa,
• Lydia Mayes,
• Patricia Williams,
• Rachel Holston,
• Kathleen Conway,
• Sharon Edmiston,
• and Allan René de Cotret

Polymorphisms in the ICAM Gene Locus are not Associated with Breast Cancer Risk

• David G. Cox,
• Susan E. Hankinson,
• and David J. Hunter

No Evidence For Large-scale Germline Genomic Aberrations in Hereditary Bladder Cancer Patients with High-Resolution Array-Based Comparative Genomic Hybridization

• Lambertus A. Kiemeney,
• Roland P. Kuiper,
• Rolph Pfundt,
• Simon van Reijmersdal,
• Mark P. Schoenberg,
• Katja K. Aben,
• Martinus F. Niermeijer,
• J. Alfred Witjes,
• and Eric F.P.M. Schoenmakers

Note from the Editors

Expanded Publishing Model for Genetic Association Studies

• Marta Gwinn and
• Muin J. Khoury

Journals Should Publish All “Null” Results and Should Sparingly Publish “Positive” Results

• John P.A. Ioannidis

Correction for vol 14, p 2591

Correction for vol 14, p 2665