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Cancer Epidemiology Biomarkers & Prevention 17, 2970, November 1, 2008. doi: 10.1158/1055-9965.EPI-08-0571
© 2008 American Association for Cancer Research
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Review

Infectious Agents and Colorectal Cancer: A Review of Helicobacter pylori, Streptococcus bovis, JC Virus, and Human Papillomavirus

Andrea N. Burnett-Hartman1,2, Polly A. Newcomb2 and John D. Potter2

1 Department of Epidemiology, School of Public Health and Community Medicine, University of Washington; 2 Fred Hutchinson Cancer Research Center, Seattle, Washington

Requests for reprints: Andrea N. Burnett-Hartman, Department of Epidemiology, School of Public Health and Community Medicine, University of Washington, 1100 Fairview Avenue North, M4-B402, Seattle, WA 98109. Phone: 206-667-2126; Fax: 206-667-5977. E-mail: anbh{at}u.washington.edu

Based on the high volume of bacteria and viruses that the intestine is exposed to and the importance of infectious agents in some gastrointestinal and anogenital cancers, it is not surprising the many studies have evaluated the association between colorectal cancer and infectious agents. This review highlights investigations of four agents in relation to colorectal cancer. Helicobacter pylori, Streptococcus bovis, JC virus, and human papillomavirus have all been evaluated as possible etiologic agents for colorectal cancer. For each of these agents, a review of possible mechanisms for carcinogenesis and epidemiologic evidence is discussed, and future directions for research are proposed. (Cancer Epidemiol Biomarkers Prev 2008;17(11):2970–79)




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HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Cancer Research Clinical Cancer Research
Cancer Epidemiology Biomarkers & Prevention Molecular Cancer Therapeutics
Molecular Cancer Research Cancer Prevention Research
Cancer Prevention Journals Portal Cancer Reviews Online
Annual Meeting Education Book Meeting Abstracts Online
Copyright © 2008 by the American Association for Cancer Research.