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Establishing a Cancer Center Data Bank and Biorepository for Multidisciplinary Research

¹ Department of Epidemiology and ² Division of Cancer Prevention and Population Sciences, Roswell Park Cancer Institute, Buffalo, New York

Requests for reprints: Christine B. Ambrosone, Department of Epidemiology, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263. Phone: 716-845-1350; Fax: 716-845-8125. E-mail: Christine.Ambrosone{at}roswellpark.org

The establishment of a biorepository with linkage to clinical and epidemiologic data will provide an invaluable resource for cancer research, including studies of cancer etiology, progression, and prognosis, as well as development of biomarkers for early detection. Developing an infrastructure for a biorepository linked to clinical, pathologic, and epidemiologic data requires significant efforts in strategic planning for efficient means to ascertain, identify, and consent participants, as well as guidelines for blood collection, processing, and storage while maintaining participant privacy rights. In this report, we present an approach to developing a Data Bank and Biorepository at our own institution, with discussion of elements to be considered when establishing such a bank. (Cancer Epidemiol Biomarkers Prev 2006;15(9):1575–7)