Cancer Epidemiology Biomarkers & Prevention, Vol 1, Issue 4 269-275, Copyright © 1992 by American Association for Cancer Research

ARTICLES

The association of diet, obesity, and breast cancer in Hawaii

MT Goodman, AM Nomura, LR Wilkens and J Hankin
Epidemiology Program, University of Hawaii, Honolulu 96813.

A case-control study of the association of dietary fat and animal protein consumption with breast cancer was conducted between 1975 and 1980 on Oahu, Hawaii. Data from this study were used to explore the relation of selected foods and the interaction of nutrients and foods with other factors, such as body size, age at menopause, and ethnicity on the risk for breast cancer. The sample included 272 postmenopausal breast cancer cases and 296 neighborhood controls. Study participants included Japanese and Caucasian women, aged 45 to 74, who were residents of Oahu. There was a suggestion of a positive-dose response relation (P < 0.01) between sausage consumption and the odds ratio for breast cancer. Significant odds ratios for breast cancer were also found for higher intakes (above the 50th percentile) of diary items, sausage, and all meats combined. The dose-response relation for nutrients and foods tended to be stronger among women with a high Benn's index (kg/cm1.5182) compared to women with a low Benn's index. In general, subjects with high dietary intakes of fat and animal protein who were in the upper 50th percentile of body size were at the greatest risk for breast cancer. However, there was no evidence for an interaction between the dietary variables and body size, ethnic group, age at menarche, age at menopause, or age at first birth that would affect the odds ratio for breast cancer. These data suggest that women with both a high intake of foods rich in fat and animal protein and with a large body size are at increased risk for breast cancer.

This article has been cited by other articles:

				A. Tavani, L. Giordano, S. Gallus, R. Talamini, S. Franceschi, A. Giacosa, M. Montella, and C. La Vecchia Consumption of sweet foods and breast cancer risk in Italy Ann. Onc., February 1, 2006; 17(2): 341 - 345. [Abstract] [Full Text] [PDF]

				P. D. Terry, J. B. Terry, and T. E. Rohan Long-Chain (n-3) Fatty Acid Intake and Risk of Cancers of the Breast and the Prostate: Recent Epidemiological Studies, Biological Mechanisms, and Directions for Future Research J. Nutr., December 1, 2004; 134(12): 3412S - 3420S. [Abstract] [Full Text] [PDF]

				P. G Moorman and P. D Terry Consumption of dairy products and the risk of breast cancer: a review of the literature Am. J. Clinical Nutrition, July 1, 2004; 80(1): 5 - 14. [Abstract] [Full Text] [PDF]

				P. D Terry, T. E Rohan, and A. Wolk Intakes of fish and marine fatty acids and the risks of cancers of the breast and prostate and of other hormone-related cancers: a review of the epidemiologic evidence Am. J. Clinical Nutrition, March 1, 2003; 77(3): 532 - 543. [Abstract] [Full Text] [PDF]

				L.-J. W. Lu, K. E. Anderson, J. J. Grady, and M. Nagamani Effects of an Isoflavone-Free Soy Diet on Ovarian Hormones in Premenopausal Women J. Clin. Endocrinol. Metab., July 1, 2001; 86(7): 3045 - 3052. [Abstract] [Full Text] [PDF]

				G. H. Rauscher, S. T. Mayne, and D. T. Janerich Relation between Body Mass Index and Lung Cancer Risk in Men and Women Never and Former Smokers Am. J. Epidemiol., September 15, 2000; 152(6): 506 - 513. [Abstract] [Full Text] [PDF]